The site is temporarily down due to maintenance. Sorry for the inconvenience.
The site is temporarily down due to maintenance. Sorry for the inconvenience.
Quality & Accuracy
Experience
The latest technologies
Speed &
Credibility
₾170.00
NT-proBNP N-Terminal Pro B-type natriuretic peptide
According to the latest definition, heart failure is a condition whose development is related to structural or functional pathology of the cardiovascular system. The condition includes at least one of the following symptoms/signs: increased serum natriuretic factor levels, presence of hemodynamic and/or imaging evidence of pulmonary or congestive heart failure, at rest or with exercise.
Diagnosing heart failure at an early stage is often difficult, because the symptoms expressed at this stage: dyspnea (shortness of breath), weakness and peripheral edema - are non-specific signs. Diagnosis is even more complicated in elderly and obese people. Ultrasound examination of the heart is the most common method at this time. Cardiac biomarkers provide an opportunity to diagnose the disease at an early stage.
The clinical significance of natriuretic peptides has long been established. They are a family of molecules represented by ANP-A type (ventricle), BNP-B type (brain) and CNP-C type natriuretic peptides. Their role is to maintain the homeostasis of circulating blood. ANP and BNP affect water-electrolyte balance.
The A-type natriuretic peptide ANP is rapidly released into the circulation, whereas the B-type is produced as precursors (pre-pro-BNP and pro-BNP) and released from the ventricular myocardium after prolonged parietal (ventricular wall) stress. (The parietal stress is the force against the heart cells).
PRO-BNP breaks down into biologically active form – BNP-B type natriuretic peptide and inactive NT-probnp.
It has been established that BNP (and consequently NT-pro-BNP) correlates with left ventricular failure.
The heart's pump function is quantified by estimating the left ventricular ejection fraction. It is defined as the ratio of the stroke volume at the end of diastole (relaxation of the ventricle) to the volume of blood retained in the left ventricle.
A normal ejection fraction is 50-65%, and less than 50% is indicative of heart damage.
Determination of natriuretic peptide, including NT-proBNP, is a biomarker for the assessment of heart failure. An increase in indicators indicates an increase in heart failure and an increase in the risk of death.
Referral norms
Data under <18 years have no clinical value
18-44 years old - 44 pg/ml
45-54 years old - 58 pg/ml
65-74 years old - 161 pg/ml
> 75 pg/ml above 346 years old
When is the survey conducted?
Determination of N-terminal pro-B-type natriuretic peptide is important in the diagnostics of conditions such as:
Preliminary preparation: it is not necessary
Study sample: Venous blood
Other tests
Testing process
Purchase a test |
Submission of material |
Results Online |
Consult a doctor |
More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
Contact information
Address: Tsinandali St. N9 (N1 Clinical Hospital area)
2021 – 2023 © Synevo. all rights reserved