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D-dimer | Laboratory research

Known as: D-dimer | Laboratory research
SKU: 1127

49.50

Study material: Venous blood
Response time (working day): 1
The test is done on an empty stomach: Yes
Home call service: Yes
Country: Georgia

General Information

**** test Is done in a week once  - on Friday

Plasmin-induced fibrin colt degradation produces fragments containing D-dimers. Thus, D-dimer It is considered a marker of hypercoagulation and endogenous fibrinolysis and its increased level is noted in patients with thrombosis.

When should we take the test?

  • The test has a negative predictive value For deep vein thrombosis of the lower extremities and pulmonary thromboembolism In the sense that getting a negative result in suspicious patients eliminates the presence of these diseases by at least 90%.
  • D-dimer during pregnancy. Its level increases gradually during pregnancy and has a poor prognostic value to rule out the diagnostics of deep vein thrombosis after 20 weeks of gestation. During childbirth, the D-dimer usually increases too much, then decreases rapidly within 3 days of delivery, and slowly returns to normal values ​​after about 4 weeks. From this point on, the test returns to its meaning.
  • Determining the risk of thrombosis recurrence In patients with a history of unprovoked deep vein thrombosis and no thrombophilic disorders;
  • Common Intravascular Coagulation Syndrome (DIC). Recommended to confirm / rule out diagnostic suspicion, assess potential risk in patients with DIC, and monitor ongoing therapy.
  • Monitoring the quality of thrombus lysis during thrombolytic therapy.
  • Suspected acute aortic dissection.
  • Determining the probability of survival of patients with chronic atrial fibrillation For the next 2 years.
  • Independent risk factor for cardiovascular mortality; which can be used to stratify groups at risk for patients with heart failure.
  • Potential risk factor for coronary heart disease.
  • Marker of subclinical thrombophilia.
  • Unexplained primary or secondary infertility and thrombophilia.
  • Breast cancer We have high levels of D-dimer on the face in patients with cancer, depending on the stage of the tumor, which is useful for the identification of lymph node metastases in patients with operative cancer.

The test is prescribed by a doctor.

Possible interpretation of the results

The increase in D-dimers is related to the following conditions:

  • DIC syndrome
  • Arterial or venous thrombosis
  • Kidney or liver failure
  • Pulmonary embolism
  • Preeclampsia
  • Myocardial infarction
  • Tumors
  • Inflammation
  • Severe infections
  • Tissue plasminogen activator therapy

Limitations

An increase in D-dimer levels may be detected

  • During a normal pregnancy
  • During estrogen therapy
  • While taking oral contraceptives
  • In the elderly
  • After the injury
  • After postoperative stress

D-dimer concentrations increase with increasing ovarian cancer marker CA-125 marker.

The presence of rheumatoid factor may interfere with the determination of D-dimer and lead to false positive results.

Additional information

How to prepare for the test?

No prior preparation is required. It is recommended to take the test in the morning on an empty stomach.

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Testing process

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Purchase a test

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Results Online

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49.50

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