D-dimer | Laboratory research

Reference values

D-dimer test It is a quick and effective screening to rule out thrombosis. A high reading does not always mean thrombosis, but requires additional testing.

• The test has a negative predictive value For deep vein thrombosis of the lower extremities and pulmonary thromboembolism In the sense that getting a negative result in suspicious patients eliminates the presence of these diseases by at least 90%.
• D-dimer during pregnancy. Its level increases gradually during pregnancy and has a poor prognostic value to rule out the diagnostics of deep vein thrombosis after 20 weeks of gestation. During childbirth, the D-dimer usually increases too much, then decreases rapidly within 3 days of delivery, and slowly returns to normal values ​​after about 4 weeks. From this point on, the test returns to its meaning.
• Determining the risk of thrombosis recurrence In patients with a history of unprovoked deep vein thrombosis and no thrombophilic disorders;
• Common Intravascular Coagulation Syndrome (DIC).Recommended to confirm / rule out diagnostic suspicion, assess potential risk in patients with DIC, and monitor ongoing therapy.
• Monitoring the quality of thrombus lysis during thrombolytic therapy.
• Suspected acute aortic dissection.
• Determining the probability of survival of patients with chronic atrial fibrillation For the next 2 years.
• Independent risk factor for cardiovascular mortality; which can be used to stratify groups at risk for patients with heart failure.
• Potential risk factor for coronary heart disease.
• Marker of subclinical thrombophilia.
• Unexplained primary or secondary infertility and thrombophilia.
• Breast cancer We have high levels of D-dimer on the face in patients with cancer, depending on the stage of the tumor, which is useful for the identification of lymph node metastases in patients with operative cancer.

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