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Lipase Is an enzyme that hydrolyzes triglycerides. Lipase is produced by a number of organs and tissues, and is differentiated accordingly - lipase of the stomach, pancreas, lungs, intestinal juice, leukocyte origin, etc.
The most important from a clinical point of view Pancreatic lipaseა, which plays a major role in the digestion of fats. Since the main source of lipase is the pancreas, in its diseases, the enzyme in the blood releases significantly large amounts.
In acute pancreatitis, serum lipase activity increases 4-8 hours after the onset of the disease, reaches a peak after 24 hours, and decreases after 8-14 days. The prognosis of the disease is unfavorable when the concentration of lipase is increased by 10 times or more.
The determination of lipase in pancreatitis has a higher clinical sensitivity (86%) and specificity (99%) than the amylase study. Simultaneous determination of amylase and blood lipase makes it possible to diagnose pancreatic diseases with up to 98% accuracy of cases.
Serum lipase activity is a very sensitive test in the case of acute alcoholic pancreatitis, while patients with obstruction of the bile ducts, duodenum, and pancreatic ducts are characterized by high levels of amylase. Lipase levels remain normal during ectopic pregnancy (if the pancreas is not involved in the process), ectopic pregnancy, lung cancer, and appendicitis. In purulent pancreatitis, an increase in blood lipase activity is not usually detected.
With the following symptoms:
The test should be performed on an empty stomach.
Venous blood
Lipase concentration increases:
Lipase concentration decreases:
https://spravochnik.synevo.ua/ru/klinicheskaia-himia/lipase.html
https://www.synevo.bg/lipaza/
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
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30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
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