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hGH (somatotropin) It is essential for the growth process, while in adults it plays an important role in the process of metabolism. It is synthesized in the acidophilic cells of the anterior pituitary gland, and its secretion from the granules of the intracellular deposit is regulated by the release of hypothalamic hormones - GHRH (growth hormone releasing hormone) and release of SRIF (somatotropin); Their synthesis depends on neurotransmitters such as serotonin, dopamine, norepinephrine, and growth hormone-releasing peptides. It is also excreted in response to exercise, stress, deep sleep, hypoglycemia, glucagon, insulin, thyroid hormones, estrogens, testosterone, and vasopressin.
hGH stimulates RNA production, protein synthesis, mobilization of fatty acids from depots, and has short-acting insulin antagonistic action. Prolonged elevated levels may lead to decreased glucose tolerance.
If the pituitary gland, at different stages, produces insufficient or excessive growth hormone it will lead to dwarfism and gigantism respectively. Excess amounts of growth hormone in adults will lead to acromegaly.
The test is useful for confirming hypo- or hyperpituitarism, which allows for timely initiation of appropriate therapy.
Hormone determination can be performed under both basal and stimulation conditions (physical activity, arginine, glucagon, or insulin) or inhibition (after 100 g of glucose uptake).
Lack of response or inadequate response to stimulation tests is associated with hypopituitarism.
In the case of gigantism or acromegaly, there is a lack of inhibition or incomplete inhibition after glucose uptake. Moreover, in patients with acromegaly, a paradoxical increase in hGH may be noted on the inhibition test.
hGH (somatotropin) - Marker of somatotropic function of the pituitary gland.
3 days before the analysis, exclude physical activity. The patient needs to rest for 30 minutes before taking blood.
Venous blood
Increase in somatotropin levels:
Decreased somatotropin levels:
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
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