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Systemic autoimmune rheumatic diseases are characterized by elevated levels of autoantibodies produced against intracellular proteins and nucleic acids (DNA, RNA). These are called autoantibodies Antinuclear Antibodies (ANA), Because they are directed mainly against nuclear antigens.
Detection / determination of ANA in the blood is the best screening test for the diagnostics of systemic connective tissue diseases. The prevalence of ANA in such patients is 20 to 100%.
To identify rheumatic diseases, it is important to distinguish between different antibodies in the ANA group. Two main categories of antinuclear antibodies are currently described:
1. Autoantibodies targeting DNA and histones.
2. Autoantibodies targeted - soluble nuclear antigens.
Target antigens of antinuclear antibodies are highly diverse. Therefore, if there is a positive result in the study of general antinuclear antibodies, it is necessary to test for specific antibodies that will help us diagnose a specific autoimmune disease.
Types of antinuclear antibodies:
In the presence of such symptoms as:
Testing is preferred on empty stomach .
Food, water and other products are not affected by the test results.
Venous blood
Positive result Confirms the presence of specific antibodies.
Weak signal Indicates that the presence of autoantibodies is unclear and questionable. Depending on the patient's symptoms, the test may be repeated every 1-2 months.
Negative result Indicates the absence of specific autoantibodies.
Testing process
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Submission of material |
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
Contact information
Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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