Profile of thyroid hormones I

The thyroid gland is one of the most important organs of the human endocrine system. Under the influence of TSH (thyroid stimulating hormone) the gland produces thyroid hormones: T4 (thyroxine) and T3 (triiodothyronine)

Thyroid hormones have a significant impact on the human body. In particular: on basic metabolism, oxygen consumption, energy balance, heat production.

At the initial stage it is possible to determine the functional state of the thyroid gland Thyroid (Thyroid) Hormone Profile I - Thyroid Screening Through which includes two main parameters:

Thyroid-stimulating hormone (TSH) The definition is the initial (first) test for the diagnostics of thyroid disease. Even a small change in the concentration of thyroid hormones causes a pronounced change in the concentration of TSH. Therefore, thyroid-stimulating hormone is a very specific and sensitive parameter for the control of thyroid function, as well as for the detection and exclusion of diseases of the hypothalamic-pituitary-thyroid system;
Free Thyroxine (FT4) Is a biologically active fraction of thyroxine that circulates in the blood, is not related to blood proteins and makes up 4% of total thyroxine - T0.03. Free thyroxine (FT4) is produced by the follicular cells of the thyroid gland under the influence of TSH and is regulated by the so-called negative feedback principle. It increases heat production and oxygen consumption by all tissues of the body except the brain, spleen and testicles. Stimulates the synthesis of vitamin A in the liver. Reduces the concentration of cholesterol and triglycerides in the blood; Accelerates protein metabolism; Increases urinary calcium excretion; Activates bone metabolism, but more - bone resorption; Has a positive chrono- and inotropic effect on the heart; Stimulates reticular formation and cortical processes in the central nervous system.

A combined study of free thyroxine (FT4) and thyroid-stimulating hormone (TSH) gives a more complete picture of the thyroid gland in patients who have altered thyroxine-binding globulin (TBG) levels (pregnancy, intake of androgens, estrogens, etc.).

When should I have thyroid hormone profile I?

When assessing the functional state of the thyroid gland, When thyroid damage is suspected, it is important to know that functional thyroid disorders or diseases at an early stage are not always manifested clinically, therefore, it is recommended for timely diagnostics. - Periodic screening of the thyroid gland.

The study is recommended in patients with symptoms of increased or decreased thyroid function. The test is also prescribed for people with an enlarged gland (so-called "goiter") or "nodules".

Signs of increased thyroid function:

Weight loss, on the background of normal or increased appetite
Accelerated pulse and increase in blood pressure
Gentle, warm, moist skin with a tendency to sweat
Shivering
Insomnia, emotional tension, irritability, crying
Standing in front of the eyes
Frequent urination or diarrhea

Signs of decreased thyroid function:

Weight gain, even with reduced appetite
Slowing of the heartbeat and decreased blood pressure
Pale, swollen, cold skin
Depression, drowsiness, memory impairment
Constipation
Thinning eyebrows or hair loss
Constant feeling of coldness

TSH and FT4 tests are prescribed after treatment or surgery for thyroid disease. At the beginning of treatment, the test should be performed once a month, once the exact maintenance dose is determined - once every 2-6 months.

How to prepare for the test?

Required for analysis Venous blood.

The test should be taken on empty stomach , In the morning (until about 10 o'clock). Drinking coffee and smoking before testing will seriously affect the results. It is allowed to drink 250 ml of water before testing.

Possible interpretation of the results

If the test reveals abnormalities, it may be necessary to use additional, other methods of diagnostics. for that You should definitely consult a specialist, which, taking into account the symptoms, will correctly select the appropriate examinations to make an accurate diagnostics.

If TSH is above normal, it is likely that FT4 will be in the normal range or if it is below normal - then you have hypothyroidism. Conversely - TSH is lower than normal and FT4 is at or above the norm - this is typical for glandular hyperfunction.

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When should I have thyroid hormone profile I?

How to prepare for the test?

Possible interpretation of the results

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