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₾290.00
Study material: Urine
Response time (working day): 14
The test is done on an empty stomach: no
Home call service: YesA laboratory test that allows for the assessment of metabolic processes in the body. The test is used to diagnose various inborn errors of metabolism, mitochondrial diseases, and organic acidosis. The test is especially important in children when evaluating developmental delays, seizures, recurrent vomiting, hypoglycemia, and metabolic disorders of unknown origin.
Organic acids are substances that are intermediate products of the metabolism of cellular organic components – amino acids, lipids, carbohydrates, nucleic acids, steroids.
Organic acidosis is a group of genetic metabolic diseases characterized by either the production of abnormal metabolites or the accumulation of normal metabolites in the body.
These disorders may manifest both in infancy and later in life as periodic episodes of metabolic decompensation and developmental delay.
Organic acids are excreted in the urine, so their determination in urine provides a more accurate answer than in plasma.
Research material – Spontaneous urination
Detection of pathological indicators of organic acids in urine is insufficient for the diagnostics of hereditary metabolic disorders. Additional diagnostic studies are necessary (e.g. molecular analysis, in vitro enzyme tests, etc.).
In hereditary organic aciduria, especially in infants and young children, it is also necessary to study plasma amino acids, since the symptoms of some aminoacidemias are exactly identical.
Because metabolic disorders are difficult to detect, it is necessary to conduct research during periods of exacerbation of the disease.
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