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Uric acid (24 hour urine)

Known as: Uric acid (24 hour urine)
SKU: 1919


Research material: 24-hour urine
Response time (working day): 1
The test is done on an empty stomach: no
Home call service: No.
Country: Georgia

General Information

Determination of uric acid excretion in urine is mainly useful in patients with kidney stones. Uric acid lithiasis can develop in both primary gout and secondary hyperuricemia (eg in malignant tumors). Urinary acid nephrolithiasis can complicate ulcerative colitis, Crohn’s disease, and jejunal bypass surgery.

When should we take the test?

  • Gout;
  • Nephrolithiasis.

Possible interpretation of the results

The concentration of uric acid in the urine increases:

  • Nephrolithiasis;
  • Leukemia;
  • Lash-Nihan syndrome;
  • Viral hepatitis;
  • Wilson disease.

The concentration of uric acid in the urine decreases:

  • Chronic kidney disease;
  • Xanthinuria;
  • Folic acid deficiency;
  • Lead poisoning.

Additional information

Hereditary deficiency of the enzyme hypoxanthine-guanine-phosphoribosyltransferase (HPRT) in young patients with gouty arthritis and nephrolithiasis or those who excrete 1000 mg of uric acid / 24 hours a day. The uric acid / creatinine ratio in morning urine samples is used to diagnose Les-Nihan syndrome, which is associated with a complete lack of enzyme activity. To detect partial deficiency of the same enzyme in adult patients with gout, this test can also be used on 24-hour urine samples.

The uric acid / creatinine ratio in spontaneous urine may also be helpful in secondary differentiation of acute renal failure due to gouty nephropathy.


How to prepare for the test?

Patient training is not required.

Study material / urine collection rule

24-hour urine. At 7 o'clock in the morning the patient urinates and does not store this urine, and during the next urination he collects the whole volume of urine in a plastic container (2-3 liter urine container) until 7 o'clock in the morning of the next day (24 hours); The patient should transfer 100 ml of urine from this container (e.g. with a syringe) to a disposable plastic cup for urine and should be stored at 2-8 ° C before the test (1-1,5 h).


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Acid uric urine


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