Total protein Laboratory research

Possible interpretation of the results

Increase total protein concentration:

• Dehydration: in case of severe injuries, burns, cholera;
• Acute, chronic infections;
• Paraproteinemia: Multiple myeloma, Waldenstrom's disease;
• Sarcoidosis and other granulomatous diseases;
• Collagenosis and rheumatoid arthritis;
• Tropical diseases: Kala-azar - Indian visceral leishmaniasis, leprosy;
• Hyperimmunoglobulinemia, mono- and polyclonal tests;
• Prolonged use of the tourniquet on the forearm veins;
• Changing body position from horizontal to vertical can increase protein concentration by approximately 30% in 10 minutes;
• Active physical activity can lead to an increase in the indicator of up to 10%.

Decreased total protein concentration:

• Insufficient protein intake: fasting, diet without protein;
• Increased protein loss: kidney disease, blood loss, burns, neoplasms, diabetes, ascites;
• Disorders of protein production due to insufficient liver function: cirrhosis of the liver, toxic liver damage, hepatitis;
• Long-term treatment with glucocorticosteroids;
• Malabsorption: enteritis, enterocolitis, pancreatitis;
• Enhancement of protein breakdown processes: fever and intoxication;
• Hypothyroidism;
• Pregnancy (especially in the 3rd trimester), lactation;
• Early childhood;
• Long bed rest;
• Rapid fluid intake;
• Prolonged immobilization after injury;
• Surgical interventions.