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Total protein Laboratory research

Known as: Total protein
SKU: 1047

13.50

Study material: Venous blood
Response time (working day): 1
The test is done on an empty stomach: Yes
Home call service: Yes
Country: Georgia

General Information

Plasma contains more than 300 different proteins: enzymes, enzyme inhibitors, blood coagulation factors, antibodies, transport proteins. Synthesis of blood plasma proteins occurs mainly in liver cells and the reticuloendothelial system. The concentration of total protein in serum mainly depends on the synthesis and breakdown of two major protein fractions - albumin and globulins. The speed of protein synthesis in the human body is influenced by many factors: the nature of nutrition, food absorption, intoxication, loss of protein due to bleeding, wound discharge, loss of protein in the urine.

When should we take the test?

  • Acute and chronic infections;
  • Collagenoses;
  • Liver and kidney pathologies; VC
  • Oncological diseases;
  • Eating disorders;
  • Thermal burns;
  • Dehydration.

Possible interpretation of the results

Increase total protein concentration:

  • Dehydration: in case of severe injuries, burns, cholera;
  • Acute, chronic infections;
  • Paraproteinemia: Multiple myeloma, Waldenstrom's disease;
  • Sarcoidosis and other granulomatous diseases;
  • Collagenosis and rheumatoid arthritis;
  • Tropical diseases: Kala-azar - Indian visceral leishmaniasis, leprosy;
  • Hyperimmunoglobulinemia, mono- and polyclonal tests;
  • Prolonged use of the tourniquet on the forearm veins;
  • Changing body position from horizontal to vertical can increase protein concentration by approximately 30% in 10 minutes;
  • Active physical activity can lead to an increase in the indicator of up to 10%.

Decreased total protein concentration:

  • Insufficient protein intake: fasting, diet without protein;
  • Increased protein loss: kidney disease, blood loss, burns, neoplasms, diabetes, ascites;
  • Disorders of protein production due to insufficient liver function: cirrhosis of the liver, toxic liver damage, hepatitis;
  • Long-term treatment with glucocorticosteroids;
  • Malabsorption: enteritis, enterocolitis, pancreatitis;
  • Enhancement of protein breakdown processes: fever and intoxication;
  • Hypothyroidism;
  • Pregnancy (especially in the 3rd trimester), lactation;
  • Early childhood;
  • Long bed rest;
  • Rapid fluid intake;
  • Prolonged immobilization after injury;
  • Surgical interventions.

Additional information

Plasma protein functions: maintenance of colloidal-oncological pressure, active participation in blood coagulation processes, constant maintenance of blood pH (integral part of the buffer system), transport function - transfer of lipids, bilirubin, steroid hormones to tissues and organs; Participate in immune reactions, maintain blood cation levels, amino acid reserve function and regulatory function (proteins are part of hormones, enzymes and other biologically active substances).

Total protein content is an important diagnostic parameter in many diseases, especially severe metabolic disorders. This test determines the integrity of circulating whey proteins that can undergo changes in both physiological and pathological conditions.

How should we prepare for the test?

Fasting is recommended for the test.

It is recommended to limit alcohol intake, smoking and strenuous physical activity for at least 12 hours before the test.

Research material

Venous blood.

 

Resources

https://spravochnik.synevo.ua/ru/klinicheskaia-himia/belok-obshiy.html

Testing process

Purchase a test Submission of material

Purchase a test

Submission of material

Results Online Consult a doctor

Results Online

Consult a doctor

Resources

https://spravochnik.synevo.ua/ru/klinicheskaia-himia/belok-obshiy.html

https://spravochnik.synevo.ua/ru/klinicheskaia-himia/belok-obshiy.html

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