Country: Georgia
Laboratories❯
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Original price was: ₾32.00.₾28.80Current price is: ₾28.80.
Study material: Venous blood
Response time (working day): 1-2
The test is done on an empty stomach: Yes
Home call service: YesThyroid Stimulating Hormone (TSH) Is a glycoprotein produced in basophilic cells of the anterior pituitary gland. TSH is released by a negative feedback mechanism in response to changes in the concentration of free triiodothyronine and free thyroxine. It consists of two chains - α and β. The α chain is common for TSH, follicle-stimulating hormone (FSH), melatoninizing hormone (LH), and chorionic gonadotropin-releasing hormone (hCG). The beta chain is different and determines its biochemical specificity. TSH has a circadian rhythm of secretion controlled by hypothalamic-releasing TSH-releasing hormone (TRH).
TSH levels are high In primary hypothyroidism.
If there are obvious signs of hypothyroidism but TSH levels are not elevated, secondary (central) hypothyroidism is suspected in hypopituitarism. In this case the biological activity of TSH is low.
Decreased levels of TSH Found in hyperthyroidism.
It is observed in pregnant women TSH tendency to decrease.
The incidence of TSH inhibition in hospitalized patients is twice as high as in patients with hyperthyroidism in patients without thyroid disease.
The concentration of TSH increases slightlyWith age A.
The production of TSH by the pituitary gland is a central regulatory mechanism for the biological action of thyroid hormones. TSH interacts with specific receptors on the surface of thyroid cells and causes two main effects: cell reproduction and hypertrophy and stimulation of the synthesis and secretion of triiodothyronine and thyroxine by the thyroid gland.
Determination of TSH is the initial test in the diagnostics of thyroid disorders. Even a small change in the concentration of thyroid hormones causes a change in the concentration of TSH. Thus, TSH is a very specific and sensitive parameter in the control of thyroid function as well as in diseases of the hypothalamus-pituitary-thyroid gland.
TSH levels are high during primary hypothyroidism (impaired thyroid function), which is the most sensitive test for this condition. If there are obvious signs of hypothyroidism but TSH levels are not elevated, secondary hypothyroidism during hypopituitarism is unlikely. Decreased levels of TSH are found in hyperthyroidism. Determination of TSH is useful for monitoring treatment in patients with hypothyroidism: low values are found in case of overdose of thyroid hormone replacement drugs, while normal values indicate balanced treatment.
With age, the concentration of TSH increases slightly, and the amount of hormones secreted at night - decreases. The normal rhythm of secretion is disturbed when waking up at night.
Decreased TSH is observed in 20% of cases during pregnancy due to an increase in hCG. Transient thyrotoxicosis syndrome is often associated with uncontrolled vomiting in pregnant women. Decreased TSH levels are observed in hydatidiform mole and choriocarcinoma due to a significant increase in hCG levels. In secondary hypothyroidism (central) TSH levels may be normal, but its biological activity is impaired.
Hypothyroidism should be ruled out during hyperprolactinemia.
Testing is preferred on empty stomach ;
The test is not performed after a thyroid biopsy or surgery on it.
TSH levels are constantly changing throughout the day; Its concentration reaches a maximum at 23:00.
Venous blood
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
Contact information
Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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