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Tacrolimus is a macrolide antibiotic with a mechanism of action similar to cyclosporine, but with a more potent effect. The medication is used in organ transplantation to prevent graft rejection.
Tacrolimus is metabolized in the liver by the enzyme cytochrome P3A4. CYP3A4 is an important enzyme involved in drug metabolism. It is inhibited (blocked) by: calcium channel blockers, antifungal agents, some antibiotics. Rifampicin and some anticonvulsants increase the enzymatic activity of cytochrome P3A4.
Material for examination: Since 90% of tacrolimus is found in cellular components of blood, the test material is whole blood.
Reference limits: 3-20 ng/l
The test sample should be collected no earlier than 5 days after the last dose of the medication.
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
56 laboratory centers in 27 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestaponi, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura, Kabali village, Dusheti, Kareli, Tianeti, Senaki, Lanchkhuti.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2024, the Synevo Georgia network will include 3 clinical laboratories and 56 blood sampling units, which will perform more than 300,000 tests.
Contact information
Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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