Standard antiphospholipid panel

General Information

For research Pattern Taking It will happen:

• In the regions: Monday   
• In Tbilisi: On Monday or/And on Tuesday (Of the day first in half)

Samples Send Will be implemented On Tuesdays,Of the day second Halfway! For this, Sample Sent Central in the laboratory Should To be sent  Tuesday at 12:00till

Antiphospholipid syndrome is an autoimmune disease whose clinical manifestations are associated with arterial and venous thrombosis, spontaneous abortions, rash, chronic headaches, dementia, seizures, and more.

Diagnosis is based on anamnestic data and the detection of antiphospholipid antibodies in the blood, which are:

• Cardiolipin antibodies IgM, IgG
• Antibodies to beta-2-glycoprotein
• Anticoagulant for lupus erythematosus

Anticardiolipin antibodies are one of a group of antiphospholipid antibodies. Antiphospholipid syndrome is characterized by a wide variety of symptoms. Antiphospholipid antibodies are also found in some infections and neoplastic diseases. In phospholipid syndrome, anticardiolipin antibodies are often associated with B2-glycoprotein-1 autoantibodies. Anticardiolipin antibodies are represented by IgM, IgG, and IgA classes. IgG is the most common form.

Lupus anticoagulants are mainly class M and G autoantibodies that bind to negatively charged phospholipid binding proteins, prothrombin, and beta2-glycoprotein 1. Lupus anticoagulant prolongs coagulation time and ultimately causes thrombus formation.

Beta-2 glycoprotein 1 autoantibodies also belong to the antiphospholipid antibodies, which are mistakenly directed against the lipid-protein structures of the membranes of one's own cells (including platelets). This study, along with other antiphospholipid antibodies (anticardiolipin antibodies and lupus anticoagulant antibodies), is performed to diagnose antiphospholipid syndrome.

When should we take the test?

In a study of primary antiphospholipid syndrome

In systemic lupus erythematosus and thrombotic complications of other connective tissue pathologies

during neurological pathologies

During thrombosis associated with pregnancy and spontaneous abortions

In unexplained thrombocytopenia

Research material

Venous blood