Country: EU
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₾110.00
Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: Yes
Home call service: Yes
hGH (somatotropin)It is essential for the growth process, while in adults it plays an important role in the process of metabolism. It is synthesized in the acidophilic cells of the anterior pituitary gland, and its secretion from the granules of the intracellular deposit is regulated by the release of hypothalamic hormones - GHRH (growth hormone releasing hormone) and release of SRIF (somatotropin); Their synthesis depends on neurotransmitters such as serotonin, dopamine, norepinephrine, and growth hormone-releasing peptides. It is also excreted in response to exercise, stress, deep sleep, hypoglycemia, glucagon, insulin, thyroid hormones, estrogens, testosterone, and vasopressin.
hGH stimulates RNA production, protein synthesis, mobilization of fatty acids from depots, and has short-acting insulin antagonistic action. Prolonged elevated levels may lead to decreased glucose tolerance.
If the pituitary gland, at different stages, produces insufficient or excessive growth hormone it will lead to dwarfism and gigantism respectively. Excess amounts of growth hormone in adults will lead to acromegaly.
hGH (somatotropin) -Marker of somatotropic function of the pituitary gland.
Increase in somatotropin levels:
Decreased somatotropin levels:
The test is useful for confirming hypo- or hyperpituitarism, which allows for timely initiation of appropriate therapy.
Hormone determination can be performed under both basal and stimulation conditions (physical activity, arginine, glucagon, or insulin) or inhibition (after 100 g of glucose uptake).
Lack of response or inadequate response to stimulation tests is associated with hypopituitarism.
In the case of gigantism or acromegaly, there is a lack of inhibition or incomplete inhibition after glucose uptake. Moreover, in patients with acromegaly, a paradoxical increase in hGH may be noted on the inhibition test.
3 days before the analysis, exclude physical activity. The patient needs to rest for 30 minutes before taking blood.
Research material: venous blood
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Testing process
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| Purchase a test | Submission of material |
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| Results Online | Consult a doctor |
