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ROMA Index Laboratory research

Known as: Ovarian Malignancy Risk Assessment Algorithm
SKU: 703

195.00

Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: Yes
Home call service: Yes
Country: EU

General Information

Roma Index (Ovarian Malignancy Risk Algorithm)

The Roma index is a reliable test for the differentiation of ovarian epithelial tumors and benign formations. It is not a stand-alone screening test for ovarian cancer. It is used to assess the risk of ovarian malignancy in the presence of bulky appendages.

 

The Roma Index, or ovarian malignancy risk assessment algorithm, combines carcinoembryonic antigen Ca-125 and human epididymal (seminal epididymal) protein 4 and assesses menopausal status and risk of ovarian malignancy in women with small pelvic masses.

Roma index can be determined: for people over 18 years of age, with bulky processes of small pelvis and ovarian appendages, when planning operative treatment. ROMA-index data are not considered independently, but in the context of clinical and radiological data.

 

The study is conducted only on women

 

 

 

 

Warning

Evaluation of the ROMA-index without clinical-radiological data is incorrect. Also, it is not an indicator for determining the need for surgical treatment.

A low rate of Roma in the initial stage does not exclude consultation with an oncologist and observation of the dynamics.

Roma-Index is not used: in women who have previously been treated for cancer, during a course of chemotherapy, in pregnant women, in young people under the age of 18.

 

When should we take the test?

During volumetric processes of the small pelvis, for differential diagnostics

Possible interpretation of the results

Ovarian carcinoma antigen CA125 <35

Human epididymal protein HE4: in premenopause: < 70; in postmenopause: < 140;

 

Interpretation of ROMA-index data

In premenopause:

< 7,4 low risk

< 25,3 high risk

in postmenopause

> 7,4 high risk

> 25,3 low risk

Reference values

 

Research method: electrochemiluminescent immunoassay

Research material: blood serum

Preparation of the patient for the study: Patients taking high doses of biotin-containing drugs (>5 mg/day) should refrain from taking the drug for at least 8 hours after taking the material.

Additional information

Testing process

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