Rodinia – Female and Male Infertility Panel in Couples (55 Genes / 40 Genes)

General Information

Rodinia – Male and Female Infertility Panel in Couples (55 Genes / 40 Genes) – The panel is the total cost of testing 2 people 4565 GEL instead of 5660 GEL

Sampling for research will be done:

• In the regions:  On Wednesday   
• In Tbilisi: on Wednesday and/or Thursday (in the first half of the day)

Samples will be shipped on Thursday afternoons! For this, the sample must be at the central laboratory by 12:00 on Thursday

What is Rodinia?

Rodinia is a study that provides screening for genetic mutations associated with infertility.

Infertility is a major pathology of the reproductive system in which conception and maintenance of pregnancy are difficult or impossible.

Worldwide, 6 in every 1 couples experience infertility. 35% of infertility cases are due to male infertility, and 45% to female infertility. The remaining cases are the result of a combination of both causes.

Infertility has many different causes, including genetic ones. Laboratory studies, ultrasound imaging, and sperm analysis reveal 65% of infertility cases. Genetic causes of infertility are observed in 10-15% of men and women.

Genetic tests for infertility investigate these causes, allowing for informed decision-making and optimal clinical management of the condition.

When is the survey conducted?

Rodinia – Genetic research for infertility can help:

• Identify genetic causes of infertility
• Provide accurate forecasting
• To determine the optimal treatment plan for the couple or individual
• Resolve the need for intervention in a timely manner

Male infertility panel (40 genes) Includes:

• X and Y chromosome research
• Detection of Y chromosome microdeletions
• The manifestation of hypogonadotropic hypogonadism (Kalman syndrome)

Female infertility panel (55 genes) Includes:

The panel tests for 55 genes as well as X chromosome aneuploidies.

Genes (male)

ANOS1, AR, AURKC, CATSPER1, CFTR, CHD7, DAZL, DDX25, DUSP6, FEZF1, FGF8, FGF17, FGFR1, FLRT3, FMR1, FSHB, FSHR, GNRH1, GNRHR, HESX1, HS6ST1, IL17RD, KISS1, KISS1R, LHB, LHCGR, NR5A1, NSMF, PRM1. PROK2, PROKR2, SEMA3A, SPRY4, SRD5A1, SRY, TAC3, TACR3, USP26, USP9Y, WDR11

Genes (female)

AIRE, ANOS1, BMP15, CAPN10, CHD7, CYP11A1, CYP17A1, CYP19A1, DENND1A, DUSP6, EIF2B2, EIF2B3, FEZF1, FGF8, FGF17, FGFR1, FIGLA, FLRT3, FMR1, FOXL2, FSHB, FSHR, GALT, GDF9, GNAS, GNRH1, GNRHR. HESX1, HS6ST1, IL17RD, INS, INSR, IRS1, IRS2, KISS1, KISS1R, LHB, LHCGR, NOBOX, NR5A1, NSMF, POF1B, POLG, PROK2, PROKR2, PSMC3IP, SEMA3A, SPRY4, STAG3, TAC3, TACR3, THADA, WDR11, WT1, ZP1