Women and health - profile

General Information

 "Women's Health Profile"  Includes 6 main parameters:

1. Thyroid-stimulating hormone (TSH) The determination is the initial (first) test for the diagnostics of thyroid disease. Even a small change in the concentration of thyroid hormones causes a marked change in the concentration of TSH. Therefore, thyroid-stimulating hormone is a very specific and sensitive parameter for evaluating the function of the thyroid gland, as well as for detecting and excluding diseases of the hypothalamic-pituitary-thyroid system;

2. Free Thyroxine (FT4)  There is a biologically active fraction of thyroxine circulating in the blood, which is not bound to blood proteins and makes up 4% of serum thyroxine - T0.03. Free thyroxine (FT4) is produced by the follicular cells of the thyroid gland under the influence of TSH and is regulated by the so-called negative feedback principle. It increases heat production and oxygen consumption by all body tissues except the brain, spleen, and testes. Stimulates the synthesis of vitamin A in the liver. reduces the concentration of cholesterol and triglycerides in the blood; accelerates protein metabolism; increases urine calcium excretion; activates bone metabolism, but more - bone resorption; has a positive chrono- and inotropic effect on the heart; Stimulates the functioning of the central nervous system.
The combined study of free thyroxine (FT4) and thyrotropic hormone (TSH) gives us a more complete picture of the thyroid gland in patients with altered thyroxine-binding globulin (TBG) levels (pregnancy, taking androgens, estrogens, salicylates, etc.)

3. Insulin It is a polypeptide hormone produced by the pancreas. by the β cells of the islets of Langerhans. Insulin molecule consists of 2 polypeptide chains: α chain - 21 amino acids and β chain - 30 amino acids, which are connected by two disulfide bridges. Insulin and C-peptide are produced as a result of enzymatic cleavage of proinsulin.
Its main role is to regulate blood glucose levels. Although insulin is mainly related to blood sugar control, it is also involved in the metabolism of fats and proteins.
When carbohydrates are eaten, the blood sugar level rises, which stimulates the production of insulin by the cells of the pancreas. Insulin converts carbohydrates into an easily digestible form for cells, cells absorb glucose and blood sugar concentration decreases.

4. Follicle-stimulating hormone (FSH) Together with malutheinizing hormone (LH), it belongs to the family of gonadotropic hormones. They are synthesized in the anterior lobe of the pituitary gland, as a result of the influence of gonadotropin-releasing (releasing) hormone from the hypothalamus.

5. Prolactin Secretion occurs by the anterior pituitary gland and is excreted episodically. Serum prolactin is found in three different forms; The predominant monomeric form (80%), which is biologically and immunologically active, is 5-20% dimeric form ("large" prolactin), which is biologically inactive, and 0,5-5% - tetrameric form (" Large-large ”prolactin), which has low biological activity.

6General analysis of blood Used to assess general health. It can also be a diagnostic indicator for many diseases such as anemia, inflammatory conditions, leukemia and others.
The erythrocyte sedimentation rate – ESR – is directly proportional to the mass of erythrocytes, the density difference between erythrocytes and plasma, and inversely proportional to plasma viscosity. Together with leukocytosis and corresponding changes in the formula of leukocytes, increased EDS is a reliable sign of the presence of infectious and inflammatory processes in the body. Measurement of EDS in autoimmune diseases allows to determine the stage of the disease (exacerbation or remission), to evaluate its activity and the effectiveness of treatment. However, an increase in EDS is not a specific indicator of this or that disease. Despite this, its changes in pathology have diagnostic and prognostic value and can become an indicator of the effectiveness of treatment.