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Prolactin | Laboratory research

Name: Prolactin | Laboratory research
Brand: სინევო
SKU: 1011
Price: 38.7 GEL
Availability: InStock
Rating: 5 (1 reviews)

Synevo editorial team

Known as: prolactin

SKU: 1011

Original price was: ₾43.00.Current price is: ₾38.70.

Study material: Venous blood

Response time (working day): 1-2

The test is done on an empty stomach: Yes

Home call service: Yes

Country: Georgia

Laboratories❯

General Information

Prolactin (PRL) is a hormone produced by the lactotropic cells of the human pituitary gland, the anterior part of the adenohypophysis. Its release is regulated by the hypothalamus. Dopamine is considered to be the main prolactin inhibitory factor and thus regulates prolactin secretion.

Prolactin is secreted by the anterior pituitary gland and released episodically. Prolactin is found in serum in three different forms; Among them, the monomeric form prevails (80%), which is biologically and immunologically active, 5-20% is the dimeric form ("big" prolactin), which is biologically inactive, and 0,5-5% is the tetrameric form (" "big-big" prolactin), which has low biological activity.

When should we take the test?

In women: Unexplained headaches, visual disturbances, weaning without childbirth and breastfeeding, pain or discomfort during sexual intercourse, hair growth in unusual areas of the body and face, acne, infertility, irregular menstrual cycle.

In men: Unexplained headache, visual disturbances, decreased libido, infertility, erectile dysfunction, abnormal lack of body and facial hair, leakage of milk from the breast.

In girls: Menstrual cycle problems, milk flow from the breast.

In sons: Delayed puberty, underdevelopment of the genitals.

In both sexes, the test is done to rule out problems with the pituitary and hypothalamus.

In patients who have already been diagnosed with a pituitary adenoma, prolactin is tested to monitor the tumor response to treatment.

Possible interpretation of the results

The reason for the increase in prolactin levels may be:

Pregnancy;
Taking certain medications;
Decreased thyroid function;
Pituitary adenoma - In general, the concentration of prolactin reflects the size of the tumor. In most patients, after starting treatment, prolactin levels drop significantly and reach normal values in 60-80% of cases.

Reduced prolactin levels:

This is a very rare condition and is found in people with impaired pituitary function. May cause insufficient milk production after childbirth. Low prolactin concentrations are mostly asymptomatic, although studies have shown that patients with low prolactin concentrations may be more susceptible to infections.

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