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Samples Send Will be implemented On Tuesdays,Of the day second Halfway! For this, Sample Sent Central in the laboratory Should To be sent Tuesday at 12:00till
Plasminogen is synthesized in the liver and circulates in 2 main forms: GLU-plasminogen (containing a glutamic acid residue) and LYS-plasminogen. Tissue plasminogen activator converts inactive plasminogen into active plasmin. In addition, urokinase plasminogen activator, coagulation factors XIa and XIIa participate in the conversion of plasminogen into plasmin.
Plasmin is a protease enzyme and participates in fibrin decomposition.
Plasminogen deficiency is a genetically determined autosomal recessive pathology.
Assessment of plasminogen activity reflects various potential defects.
Referral norms are different in different ethnic groups.
The normal concentration of plasminogen in newborns is much lower.
Chromogenic study of plasminogen: is a semi-functional study of plasminogen activity. During the study, plasminogen is activated through streptokinase, which converts it into plasmin. A plasminogen functional assay determines whether plasminogen deficiency is present. If the functional test reveals a reduced activity of plasminogen, then an antigen test is performed to detect the first and second type of disorder.
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