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Elastase is a proteolytic enzyme produced by the exocrine tissue of the pancreas. During the test, the amount of elastase in the blood is determined to assess how well a person's pancreas is functioning.
The pancreas is located in the abdominal cavity and consists of two types - exocrine and endocrine tissue. The exocrine pancreas is responsible for the production of elastase along with other enzymes that are transported in the small intestine to break down fats, proteins and carbohydrates as part of digestion.
The test determines the level of elastase 1 to diagnose/rule out an inflammatory episode of acute pancreatitis or chronic pancreatitis 2.
Unlike other enzymes used in the diagnostics of acute pancreatitis (amylases, lipases), determination of pancreatic elastase in serum has the following advantages:
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