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Neisseria gonorrhoeae DNA | PCR (urine, urogenital swab)

Name: Neisseria gonorrhoeae DNA | PCR (urine, urogenital swab)
Brand: სინევო
SKU: 332
Price: 350 GEL
Availability: OutOfStock
Rating: 5 (1 reviews)

Synevo editorial team

Known as: Neisseria gonorrhoeae DNA PJR (urine, vaginal and urethral smear)

SKU: 332

₾350.00

Not in stock

Research material: urine, vaginal and urethral smear

Response time (working day): 14

The test is done on an empty stomach: no

Home call service: No.

Country: EU

Laboratories❯

General Information

A vaginal swab can be taken for research:

"Synevo" in the Varketili branch. Miss: Sukhishvili N1, every day except Sundays:

Monday-Friday 10: 30-17: 00

Saturday 10: 30-14: 00

"Synevo" Dolidze branch. Miss: Dolidze N46 every day, except Sundays:

Monday-Friday 10: 30-17: 00

Saturday 09: 00-14: 00

The cost of taking a smear is 15 GEL

**** Test is done once a week - Friday

Gonococcal infection (gonorrhea)Is Sexually transmitted diseaseCaused by Gram-negative bacteria - Neisseria gonorrhoeae. In Europe, gonorrhea is second in frequency (after chlamydial infection), but the true prevalence is unknown due to the relatively high percentage of asymptomatic forms. It is known that gonorrhea is diagnosed 3 times more often in men than in women (this is partly due to a clearer clinical picture and timely diagnostics).

The main route of transmission is sexual contact, in rare cases transmission is possible through personal hygiene and intranatally, through the birth canal.

Currently, the most common method of diagnosing gonococcal infection remains the method of molecular diagnostics - polymerase chain reaction (PCR). This method allows the identification and appointment of treatment for N. gonorrhoeae in a short time with high diagnostic sensitivity and specificity (more than 96%).

PCR for the diagnostics of Neisseria gonorrhoeae is recommended:

In men The first part of the morning urine is using. This is the most optimal material in which case the diagnostic sensitivity reaches 85% -95%.
Consumption of the first part of urine in women has a lower diagnostic sensitivity (about 80-90%) than in men, so in the case of women Urogenital smear Recognized as the most optimal material for testing. The study of the first part of the urine in women can be used in situations where it is difficult to take a smear from the vagina and cervix (for example, in pregnant women) or in the face of a cystitis clinic (including chronic). It is the most optimal time to examine women The fourth week from the first day of the last menstrual period.
You can pick up a smear brush and Eppendorf with transport fluid at Synevo branches.
To take a smear, contact a doctor-specialist (urologist, gynecologist).

The research material should be brought to the laboratory by 13:00.

How to prepare for the test?

Before taking smear:

Do not use a vaginal shower;
It is recommended to abstain from sexual intercourse for at least 24-48 hours;
Do not urinate directly before smearing;
Contraceptive use should be discontinued three days in advance;
The smear is taken 24-48 hours after the colposcopy and 24 hours after the vaginal ultrasound examination;

Perform external genital hygiene procedures without the use of soap and other detergents;
The test may be performed no earlier than 10-14 days after completion of antibacterial, antifungal, or topical antiseptics;
It is recommended to perform the test during ovulation or in the presence of symptoms of inflammatory disease of the urogenital tract.
Examination isn't performing during menstrual bleeding.
The examination is performing 2 weeks after taking preparations containing microorganisms (probiotics, eubiotoc).

When should we take the test?

Exclusion of Neisseria gonorrhoeae as the cause of urethritis, vaginitis, and cervicitis in women;
Exclusion of Neisseria gonorrhoeae as the cause of urethritis, epididymitis, orchitis in men;
Exclusion of Neisseria gonorrhoeae in the diagnostics of trichomoniasis and other STDs;
Exclusion of Neisseria gonorrhoeae in all cases of infertility (men and women);
The presence of conjunctivitis in the newborn involves examination of both the newborn and the mother;
Conjunctivitis in adults;
Proctitis Clinic;
Pharyngitis of unknown etiology;
Monitor the effectiveness of treatment (no earlier than 3 weeks after the end of treatment).

In men with symptoms such as:

Burning and discomfort when urinating, redness;
Pain, heaviness and discomfort in the testicles;
Genital discharge.

In women with symptoms such as:

Pain when urinating;
Vaginal discharge;
Bleeding after intercourse, as well as between regular menstrual periods;
Abdominal and pelvic pain;

Possible interpretation of the results

The study material identified Neisseria gonorrhoeae:

Neisseria gonorrhoeae is the etiological cause of the clinical manifestations.

The study material does not reveal Neisseria gonorrhoeae:

Infection is not noted;
Neisseria gonorrhoeae cannot be detected in the study material;
Small amount of pathogen (its level is below analytical susceptibility);
False-negative result in the presence of PCR test inhibitors in the study material.

Reference values

Neisseria is characterized by tropism to the epithelium of the vagina, urethra, endocervical canal, rectum, larynx, conjunctiva. As a result of bacteremia (occurs in less than 1% of cases), peritoneal inflammation may develop. Asymptomatic transmission of the infection, which contributes to the development of complications due to the lack of treatment, is characteristic of 50-90% of women and 10% of men. It should be noted that Neisseria gonorrhoeae is associated with an increased risk of developing other sexually transmitted infections, especially T. vaginalis.

The main manifestation of gonococcal infection in men is urethritis, which can lead to the development of the following complications: prostatitis, vesiculitis, epididymitis, paraurethritis, periurethritis, etc. Infertility may develop.

In women, according to the localization of the inflammatory process, there are:

Gonococcal infection of the lower parts of the genitourinary system (cervicitis, urethritis, cystitis, vulvovaginitis);
Inflammatory diseases of the pelvic organs (endometritis, salpingitis, oophoritis, pelvic peritonitis).

In case of chronic process and prolonged course of treatment, ectopic pregnancy and infertility may develop. Gonococcal infection in pregnant women causes premature rupture of membranes, premature birth, and fetal infection.

Other localizations of the lesion (in both men and women):

Anorectal zone;
Oropharynx;
Eye: Gonococcal ophthalmia in newborns, gonococcal conjunctivitis (gonoblenorea) usually occurs in newborns in the first hours or days of life. Infection develops when the fetus passes through the mother's infected birth canal or (in rare cases) comes into contact with the infant's maternity staff with infected hands.

Laboratory diagnostics of diseases caused by Neisseria gonorrhoeae includes direct detection methods, such as microscopic examination of stained smears, culture method with inoculation on special media, and pjr (PCR) Diagnosis (detection of pathogen DNA).

Currently, the most widely used method for diagnosing Neisseria gonorrhoeae remains the molecular diagnostic method – polymerase chain reaction (PCR). This method allows for the identification of N. gonorrhoeae in a short time with high diagnostic sensitivity and specificity (over 96%) and the appointment of treatment.

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Resources

https://www.synevo.bg/multipleksen-pcr-za-polovo-predavani-patogeni/

https://spravochnik.synevo.ua/ru/urogenitalnie-infektcii/id1098.html

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This medical information is not intended to be a universal treatment guide for all patients. The treatment process, including the type, volume, and frequency of diagnostic tests and therapeutic procedures, is determined by the physician individually — based on an assessment of the patient's condition and relevant medical indications. The decision is made in consultation with the patient. Before purchasing a test, please read the instructions for its preparation.