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Levetiracetam is a broad-spectrum antiepileptic medication used to treat partial, focal, myoclonic, tonic-clonic seizures in both adults and children. Levetiracetam binds to synaptic proteins, inhibits calcium channels at the presynaptic level and reduces neurotransmitter release. That is, it acts as a neuromodulator.
The main metabolite of levetiracetam is a carboxylic acid derivative, which is inactive and accounts for a quarter of the administered dose. The medicine is excreted by the kidneys. The half-life is 6-8 hours in adults, 5-7 in children, 10-11 hours in the elderly. In case of functional kidney failure, it is necessary to adjust the dose of the medicine and monitor the concentration.
Preparation of the patient:The test sample should be taken at least 12 hours after the last dose.
Material for examination:Venous blood
Referral norms:10-40 μg/ml
to monitor the therapeutic effect
To monitor the toxic effect of the medication
An anticonvulsant blood test is used to monitor levels of an anticonvulsant (an anti-epileptic drug). The test assesses whether the drug's concentration is within the therapeutic range, which ensures effectiveness and reduces the risk of side effects.
Toxic effects of the medication may include a decrease in hematocrit, erythrocytes, and neutrophils in the blood, drowsiness, asthenia, and dizziness.
The drug is metabolized by hepatic hydrolases.
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Testing process
| Purchase a test | Submission of material |
| Results Online | Consult a doctor |
