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Lactate dehydrogenase (LDH) Is an intracellular enzyme that is important for the production of energy in almost every cell in the body.
The highest concentrations of LDH are found in the heart, liver, muscles, kidneys, and lungs.
The test determines the concentration of LDH in the blood and in some body fluids. Only small amounts of LDH may be detected in the blood because the enzyme is secreted into the bloodstream during cell damage and death. Thus, serum lactate dehydrogenase is a nonspecific marker of tissue damage in the body.
Although the increase in LDH is nonspecific, this test is useful for confirming the diagnostics of myocardial infarction or pulmonary infarction. During myocardial infarction, elevated levels of LDH persist longer than those of other enzymes.
Determining LDH alone can not help us determine the exact cause of the injury, so its test is always combined with other tests.
Determination of blood lactate dehydrogenase:
Determination of tissue lactate dehydrogenase:
LDH concentration increases:
How to prepare for the test?
The test should be performed on an empty stomach.
Research material
Venous blood
Other conditions associated with elevated LDH levels:
LDH concentration decreases:
Adequate response to cytostatic therapy.
Other tests
Testing process
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