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Immunohistochemistry (IHC) is a laboratory technique used to determine the type and characteristics of cells of origin. The test detects specific tissue markers using special antibodies.
Immunohistochemistry is particularly important in the diagnostics of cancer. It can help to clarify the type of tumor, assess the prognosis of the disease, and detect markers that are crucial in selecting a specific treatment.
In most cases, the study is performed on tissue that has already been removed and stored in a paraffin block, so an additional biopsy is not required.
Immunohistochemical (IHC) testing on paraffin blocks is one of the most common methods for further evaluation of tumor tissue.
Immunohistochemical markers are specific proteins found on the surface, cytoplasm, or nucleus of cells.
Immunohistochemical marker research is an important part of modern personalized medicine, both for clarifying the diagnostics and selecting treatment tactics.
Storing the paraffin block allows, if necessary, additional studies to be performed without taking a new biopsy, which is more comfortable and safe for the patient.
The interpretation of the immunohistochemical study response should always be done in conjunction with the histological conclusion, clinical data, and results of other studies, as the evaluation of a single marker alone often does not provide complete diagnostic information.
Immunohistochemical (IHC) testing of tumor tissue is performed when conventional histological (microscopic) examination is not sufficient to make an accurate diagnostics. This method uses special antibodies that identify the cell type and characteristics of the tumor.
IHC testing is particularly important for determining the origin of a tumor (from which organ the metastasis developed) or for differentiating between different types of tumors.
Material for examination: Paraffin-embedded tissue block
The sample should be sent with complete existing medical documentation, including: imaging findings (CT, MRI), initial microscopic examination report, pathological diagnostics, and other related information to allow for proper identification of the paraffin block and confirmation of its correspondence with the patient's existing medical documentation.
Documentation must be submitted in English!
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Yes.
The sample will only be sent with complete existing medical documentation (imaging study (CT, MRI) results, primary microscopic examination report, pathological diagnostics, and other related information) to allow for proper identification of the paraffin block and confirmation of its correspondence with the patient's existing medical documentation.
Documentation must be submitted in English!
Testing process
| Purchase a test | Submission of material |
| Results Online | Consult a doctor |
