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Immunohistochemical examination – paraffin blocks of tumor tissue (6-9 blocks) (≥ 3 markers)

Known as: Immunohistochemical examination – paraffin blocks of tumor tissue (6-9 blocks) (≥ 3 markers)
SKU: 765

540.00

Research material: tissue block (paraffin)
Response time (working day): 14
The test is done on an empty stomach: no
Home call service: No.
Country: EU

General Information

ImmunohistochemicalResearch (IHC)

Immunohistochemistry (IHC) is a laboratory technique used to determine the type and characteristics of cells of origin. The test detects specific tissue markers using special antibodies.

Immunohistochemistry is particularly important in the diagnostics of cancer. It can help to clarify the type of tumor, assess the prognosis of the disease, and detect markers that are crucial in selecting a specific treatment.

In most cases, the study is performed on tissue that has already been removed and stored in a paraffin block, so an additional biopsy is not required.

Immunohistochemical (IHC) testing on paraffin blocks is one of the most common methods for further evaluation of tumor tissue.

 

Immunohistochemical markers

Immunohistochemical markers are specific proteins found on the surface, cytoplasm, or nucleus of cells.

Immunohistochemical marker research is an important part of modern personalized medicine, both for clarifying the diagnostics and selecting treatment tactics.

Storing the paraffin block allows, if necessary, additional studies to be performed without taking a new biopsy, which is more comfortable and safe for the patient.

 

 

Markers

 

When should we take the test?

  • For the diagnostics of cancer – IHC can be used to determine the type of tumor (for example, carcinoma, melanoma, or sarcoma) and also to identify the primary site of a tumor that has spread to other organs as metastases.
  • For determining prognosis – IHC can be used to assess how aggressive or high-risk a tumor is. It also allows for the stage and grading of the cancer, which is important for choosing the best treatment method.
  • To predict response to treatment – ​​IHC reveals characteristics of tumor tissue that indicate how effective a particular treatment may be (for example, identifying hormone-dependent tumor types – allowing for an effective treatment plan)

Possible interpretation of the results

The interpretation of the immunohistochemical study response should always be done in conjunction with the histological conclusion, clinical data, and results of other studies, as the evaluation of a single marker alone often does not provide complete diagnostic information.

Reference values

Immunohistochemical (IHC) testing of tumor tissue is performed when conventional histological (microscopic) examination is not sufficient to make an accurate diagnostics. This method uses special antibodies that identify the cell type and characteristics of the tumor.

IHC testing is particularly important for determining the origin of a tumor (from which organ the metastasis developed) or for differentiating between different types of tumors.

 

Material for examination: Paraffin-embedded tissue block

The sample should be sent with complete existing medical documentation, including: imaging findings (CT, MRI), initial microscopic examination report, pathological diagnostics, and other related information to allow for proper identification of the paraffin block and confirmation of its correspondence with the patient's existing medical documentation.

Documentation must be submitted in English!

 

 

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This medical information is not intended to be a universal treatment guide for all patients. The treatment process, including the type, volume, and frequency of diagnostic tests and therapeutic procedures, is determined by the physician individually — based on an assessment of the patient's condition and relevant medical indications. The decision is made in consultation with the patient. Before purchasing a test, please read the instructions for its preparation.
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