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Hepatitis B virus DNA – real-time PCR

Name: Hepatitis B virus DNA - real-time PCR
Brand: სინევო
SKU: 731
Price: 442 GEL
Availability: InStock
Rating: 5 (1 reviews)

Synevo editorial team

Known as: Hepatitis B virus DNA determination

SKU: 731

₾442.00

Study material: Venous blood

Response time (working day): 14

The test is done on an empty stomach: no

Home call service: Yes

Country: EU

Laboratories❯

General Information

Diagnosis of acute or chronic hepatitis B infection is based on the detection of serological markers, such as: hepatitis B virus surface S antigen (HBVSAg), hepatitis B virus COR antigen IgM antibodies, determination of hepatitis B virus DNA.

However, acute and chronic HBV infection is diagnosed by serological methods, DNA determination is necessary:

For early diagnostics in the acute stage of the disease
To differentiate between active and inactive forms of HBV
To monitor anti-HBV treatment

The presence of DNA of hepatitis B virus in the blood serum is a marker of active reproduction of the virus.

The level of HBV DNA in the blood is maximal at the peak of the acute period of the disease, then gradually decreases. In acute HBV, when the surface antigen test is equivocal, DNA testing helps to confirm the diagnostics.

When should we take the test?

In the body of patients infected with hepatitis B virus, sometimes the complete elimination of the virus does not occur and they remain positive for HBVsAg (surface antigen). Such a condition is classified as:

chronically activeHBV infection – At this time, the virus is replicating (multiplying) in the body. The patient is HBV e-antigen positive (HBeAg). The level of viral DNA in the serum is high
chronically inactiveHBV Infection - At this time, the virus does not replicate in the body. The patient is negative for HBV e-antigen (HBeAg). The level of viral DNA in serum is low.

Determination of viral DNA is important to identify the status of chronic hepatitis. Patients with chronic active hepatitis B are at increased risk of further complications of liver damage.

In reactivation of chronic inactive HBV infection (HBeAg-negative), sometimes the E antigen of the virus (a marker of viral replication) may not appear in the serum. That's why hepatitis B virus DNA testing is essential for virus detection and quantification.

Possible interpretation of the results

Quantitative range of study includes 10 to 1 IU/mL

A value < 10 IU/ml is negative, that is, virus DNA was either not found in the sample, or was detected in a minimal amount, which cannot be determined more precisely by quantitative methods. If there is a clinical need, it is recommended to repeat the study in 1-2 months.

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Testing process


Purchase a test	Submission of material


Results Online	Consult a doctor

Resources

https://microbiology.testcatalog.org/show/HBVQN

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This medical information is not intended to be a universal treatment guide for all patients. The treatment process, including the type, volume, and frequency of diagnostic tests and therapeutic procedures, is determined by the physician individually — based on an assessment of the patient's condition and relevant medical indications. The decision is made in consultation with the patient. Before purchasing a test, please read the instructions for its preparation.