Country: Georgia
Laboratories❯
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Original price was: ₾239.00.₾201.00Current price is: ₾201.00.
Research material: blood
Response time (working day): 1
The test is done on an empty stomach: Yes
Home call service: Yes
High sensitivity C reactive protein
Or creatine phosphokinase (CRK) is an enzyme that is actively involved in the energy processes of the cell.
Creatine kinase is found in high concentrations in the myocardium and skeletal muscle and in much lower concentrations in the brain. CK has a dimeric structure and is presented in 4 forms: mitochondrial isoenzyme and 3 fractions of cytosolic isoenzymes: CK-MM (muscular), CK-MB (myocardial), CK-BB (cerebral).
In healthy people, total creatine kinase levels are almost entirely represented by the isoenzyme MM (muscle creatine kinase).
Determination of creatinine kinase is recommended in all cases of muscle tissue breakdown. Of particular importance is the MB fraction, which is strictly specific to the heart muscle and is positive for all types of heart damage.
The most common cases when research is conducted are:
It is preferable to do the test on an empty stomach.
Prior to the test, the patient should avoid strenuous physical activity.
Venous blood
Creatine kinase concentration increases:
Decreased creatine kinase concentration:
It usually reflects a decrease in muscle mass associated with metastatic tumors, corticosteroid therapy, alcoholic liver disease, and collagenosis.
Is the main electrolyte (cation) and an important component of the intracellular buffer system. 90% of potassium is concentrated inside the cell and only a small amount is present in the extracellular space. The vast majority of potassium (90%) is in ionic form, the rest is associated with proteins.
Potassium plays an important role in physiological processes of muscle contraction, functional activity of the heart, conduction of nerve impulses, enzymatic processes, metabolism, maintenance of acid-base balance, osmotic pressure, protein anabolism and glycogen formation. Anabolic processes are accompanied by K+ fixation in the cell, and catabolic processes are accompanied by its release.
Potassium is one of the important indicators of water-electrolyte and acid-base balance.
Potassium concentration increases:
Potassium concentration decreases:
Is an intracellular enzyme that is important for the production of energy in almost every cell in the body.
The highest concentrations of LDH are found in the heart, liver, muscles, kidneys, and lungs.
The test determines the concentration of LDH in the blood and in some body fluids. Only small amounts of LDH may be detected in the blood because the enzyme is secreted into the bloodstream during cell damage and death. Thus, serum lactate dehydrogenase is a nonspecific marker of tissue damage in the body.
Although the increase in LDH is nonspecific, this test is useful for confirming the diagnostics of myocardial infarction or pulmonary infarction. During myocardial infarction, elevated levels of LDH persist longer than those of other enzymes.
Determining LDH alone can not help us determine the exact cause of the injury, so its test is always combined with other tests.
Determination of blood lactate dehydrogenase:
Determination of tissue lactate dehydrogenase:
The test should be performed on an empty stomach.
Venous blood
LDH concentration increases:
Other conditions associated with elevated LDH levels:
LDH concentration decreases:
Adequate response to cytostatic therapy.
Sodium is one of the important indicators of water-electrolyte and acid-base balance.
Is the main cation of the extracellular space, found in all body fluids (blood plasma, gastric, pancreatic juice, bile, intestinal juice, sweat, cerebrospinal fluid, etc.) in ionized state. Relatively large amounts of sodium are found in cartilage and slightly less in bones and make up 15-30% of the total amount of sodium in the body.
Sodium is one of the important indicators of water-electrolyte and acid-base balance.
Increase in sodium concentration:
Reduction of sodium concentration:
1. Reduction of extracellular fluid volume and total sodium:
2. Moderately elevated extracellular fluid volume and normal total sodium levels:
3. Increased extracellular fluid volume and increased total sodium levels. (Edema-related diseases):
Plasma lipids are mainly represented by fatty acids, triglycerides, cholesterol and phospholipids.
Triglycerides are lipids that are absorbed by the body through food, synthesized in the liver, intestines and adipose tissue and circulated as part of protein complexes - lipoproteins. Triglycerides are the most important reserves among the body's energy reserves, essential lipids for body fat and food, a key source of energy for cells, and an essential component of cell membranes.
Triglycerides accumulate in adipocytes, break down by hydrolysis to glycerol and fatty acids, and are excreted into the circulatory system.
In adipose tissue, they are deposited in the form of glycerol, fatty acids, and monoglycerides, which are subsequently converted in the liver to triglycerides, which are composed of VLDL (80%) (very low-density lipoprotein) and LDL (15%) (low-density lipoprotein).
Elevated triglyceride levels:
Reduced triglyceride levels:
Is a fat-like substance found in every cell of the body. It is found in blood and body tissues in free and esterified form. Free cholesterol is a component of plasma cell membranes, as well as mitochondria and endoplasmic reticulum membranes, and is a precursor to sex hormones, corticosteroids, bile acids, and vitamin D. Up to 80% of cholesterol is synthesized in the liver, while the rest enters the body through products of animal origin (fatty meat, butter, eggs). Cholesterol is insoluble in water, it is transported between tissues and organs through lipoprotein complexes. Distinguish between cholesterol fractions: low-density lipoprotein (LDL) and high-density lipoprotein (HDL), which differ in composition and function.
Estrogens lower and androgens increase total cholesterol. Cholesterol buildup is one of the major risk factors for developing cardiovascular disease (atherosclerosis and coronary heart disease). Adults have a higher risk of developing coronary artery disease when their blood cholesterol levels are above 5,22 mmol / L.
A total cholesterol test is always advisable in conjunction with the determination of triglycerides, HDL and LDL cholesterol.
Determining cholesterol levels gives us an idea of lipid status and metabolic disorders and determines the risk of developing atherosclerosis, coronary stenosis and myocardial infarction.
high-density lipoprotein (so-called "good cholesterol"), Synthesized when it enters the liver and bloodstream, it is mainly composed of apoprotein (a protein on the surface of lipoprotein that regulates lipoprotein metabolism). The main function of HDL is to bind and transport excess cholesterol from extrahepatic (outer liver) tissues to the liver for further excretion into the bile. Along with LDL, HDL is involved in maintaining cellular cholesterol levels. Because of its ability to bind and remove cholesterol, HDL is called an anti-atherogenic factor because it prevents the development of atherosclerosis, hence patients with high levels of HDL have a lower risk of developing atherosclerosis.
The test is prescribed by a doctor.
Elevated HDL levels:
Reduced HDL levels:
Low-density lipoprotein (so-called "bad" cholesterol) - Consists of proteins and lipids, mainly - cholesterol. It contains the most cholesterol (60-70% of total cholesterol in serum) and is mainly produced by the degradation of VLDL (a very low-density lipoprotein), a major transporter of triglycerides.
LDL is involved in the transport of cholesterol to tissues and the arterial system, which explains the increased risk of developing atherosclerosis and coronary heart disease in patients with elevated serum lipoprotein levels. Thus, the determination of LDL is specific for assessing the risk of cardiovascular disease and for making therapeutic decisions;
The test is prescribed by a doctor.
VLDL (very low density lipoprotein) Synthesized in the liver. Circulating free fatty acids in the liver produce triglycerides that bind to apoproteins and cholesterol and then pass into the bloodstream as VLDL. Their main function is to transport triglycerides synthesized in the liver to fat and muscle cells. They act as Precursors of LDL (low density lipoproteins). LDL Contains 60-70% of total serum cholesterol, formed as a result of the breakdown of VLDL. The major LDL protein is apoprotein B (apo-B). Although the half-life of LDL is longer (3-4 days) than that of its predecessor or VLDL, it is more abundant in circulation than VLDL. LDL cholesterol is involved in the transport of cholesterol to tissues, primarily the arterial system, which explains the high risk of developing atherosclerosis and coronary heart disease in patients with elevated levels of this lipoprotein. Thus, the determination of LDL is a specific test to assess the risk of cardiovascular disease and to determine therapeutic procedures.
Cholesterol screening is mainly done by examining the following parameters: total cholesterol, LDL Cholesterol, HDL Cholesterol and triglycerides.
Blood sampling is required for analysis (at least 12 hours after the last meal).
Some medications can affect test results, so it is important to consult your doctor and get detailed instructions to prepare for the test.
Venous blood
Reflects the ratio of atherogenic lipoproteins (LDL) to the content of antiatherogenic lipoproteins (HDL) in the blood plasma, or more accurately reflects the favorable and unfavorable combination of lipoproteins in terms of the risk of coronary artery disease.
The Plasma Atherogenic Index (AIP) is a strong marker for predicting the risk of atherosclerosis and coronary heart disease.
AIP is related to the particle size of pre- and anti-atherogenic lipoproteins. It is calculated according to the following formula – log(TG/HDL-C). An AIP value of less than 0.11 has been suggested to be associated with a lower risk of cardiovascular disease (CVD); Values between 0.11 and 0.21 and greater than 0.21 are associated with intermediate and increased risks, respectively.
The atherogenic index correlates with other risk factors for CVD. The most important risk factors are dyslipidemia, hypertension, obesity, physical inactivity, poor diet and smoking. Among them, the plasma lipid profile is a major risk factor for CVD.
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
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Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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