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Glycated Hemoglobin (HbA1c)

Known as: Glycated Hemoglobin (HbA1c)
SKU: 1080

38.70

Study material: Venous blood
Response time (working day): 1
The test is done on an empty stomach: no
Home call service: Yes
Country: Georgia

General Information

Glycated Hemoglobin (HbA1c) Is hemoglobin in which the glucose molecule condenses with the β-terminal valine (amino acid) of the β-chain of the hemoglobin molecule. Glycosylated hemoglobin represents a small percentage of hemoglobin (5-7%). It is the result of continuous and irreversible binding of glucose from the blood throughout the life of erythrocytes (approximately 100-120 days). Glycosylation occurs in two stages, through non-enzymatic reactions, depending on the level of glucose in the blood. The increase in glycated hemoglobin level is proportional to the average blood glucose concentration in the last 2-3 months before testing; Its level in the blood normalizes 4-6 weeks after the onset of euglycemia.

When should we take the test?

  • Screening, diagnostics and monitoring of the effectiveness of their treatment of diabetes mellitus and intermediate hyperglycemia;
  • Predicting the risk of developing complications of diabetes.

Possible interpretation of the results

Increase in glycated hemoglobin concentration:

  • Presence of hyperglycemia in the last 2-3 months;
  • Poorly controlled or newly diagnosed diabetes;
  • Other conditions associated with impaired glucose tolerance;
  • Iron deficiency;
  • Splenectomy;
  • Hemoglobinopathies (false increase in concentration may be caused by high concentrations of fetal hemoglobin (HbF)).

Decreased glycated hemoglobin concentration:

  • Hypoglycemia;
  • Hemolytic anemia;
  • Bleeding;
  • blood transfusion;
  • Hemoglobinopathy;
  • Pregnancy.

Additional information

The HbA1C test is used for screening, diagnostics, and long-term monitoring of glucose levels in patients with diabetes. It also plays a prognostic role in determining the risk of macro- and microvascular complications of diabetes.

Since 2010, a recommendation from the ADA (American Diabetes Association) has been used to diagnose glycated hemoglobin HbA1c with a threshold value of 6,5% or more for the diagnostics of diabetes.

Advantages of studying glycated hemoglobin (HbA1c) for the diagnostics of diabetes and prediabetes:

  • Reflects the level of glycemia for a long time, ie characterizes the state of chronic hyperglycemia.
  • Fasting testing is not required, so screening can be done at any time.
  • Does not depend on diet or emotional factors, medications and stress.

How to prepare for the test?

No specific training is required.

It is recommended to limit alcohol intake, smoking and strenuous physical activity for at least 12 hours before the test.

 

Testing process

Purchase a test Submission of material

Purchase a test

Submission of material

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Results Online

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