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Human chorionic gonadotropin (hCG) Is a glycoprotein hormone that is normally found in the blood and urine only during pregnancy. It is synthesized by placental tissue (starting with primitive trophoblasts) and prevents corpus luteum destruction in the first weeks of pregnancy. hCG or hCG-like substances are also produced by various trophoblastic or non-trophoblastic tumors.
Intact hCG consists of 2 subunits (alpha and beta subunits) that are linked by a noncovalent bond. These subunits can also be represented in a free, unrelated form. The alpha subunit has the identical structure of the homologous subunit of pituitary glycoprotein hormones (LH, FSH, and TSH). Beta subunits are specific for each of these hormones, which determines their specific biological activity. However, there are similarities between the beta subunits of hCG and LH, which explains the substantially identical biological activity of these two hormones.
hCG-free β-subunit fraction Represents about 1% of total intact hCG, it is biologically inactive. Studies have shown that the level of free fraction of the β-subunit of hCG is the most accurate marker of the presence of fetal aneuploidy in the first trimester of pregnancy.
Free beta-hCG concentration increases:
Free beta-hCG concentration decreases:
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
53 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Kabali village, Dusheti, Kareli, Tianeti.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2024, the Synevo Georgia network will include 3 clinical laboratories and 53 blood sampling units, which will perform more than 300,000 tests.
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Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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