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Ferritin | Laboratory research

Known as: Ferritin | Laboratory research
SKU: 1085

Original price was: ₾50.00.Current price is: ₾45.00.

Study material: Venous blood
Response time (working day): 1-2
The test is done on an empty stomach: no
Home call service: Yes
Country: Georgia

General Information

Ferritin - A water-soluble complex of iron hydroxide with the protein apoferritin, found in liver, spleen, bone marrow cells, reticulocytes and small amounts of blood serum, where it performs the function of transporting iron.

Ferritin concentration depends on iron supply, so this indicator is used to diagnose and monitor iron deficiency or excess, and for the differential diagnostics of anemia.

When should we take the test?

  • Differential diagnostics of anemia;
  • Assessment of iron deficiency anemia and monitoring of iron replacement therapy;
  • Diagnosis and monitoring of iron deficiency or excess;
  • Diagnosis and monitoring of oncological diseases.

Possible interpretation of the results

Ferritin levels rise:

  • On liver biopsy;
  • Secondary iron overload syndromes (blood transfusion, ineffective erythropoiesis, hemodialysis, etc.);
  • Parenchymal liver disease (cirrhosis of the liver, hepatocellular carcinoma);
  • Leukemia, lymphoma, pancreatic cancer, neuroblastoma;
  • Infectious diseases;
  • Acute and chronic inflammatory diseases;
  • Hyperthyroidism;
  • Megaloblastic, sideroblastic, hemolytic anemias, thalassemia.

Ferritin levels decrease:

  • Iron deficiency anemia;
  • Chronic diseases of various etiologies;
  • Severe bleeding;
  • Celiac disease.

Additional information

Ferritin also belongs to the acute phase proteins and its normal or increased concentration does not necessarily reflect the deposited iron supply in inflammatory diseases, malignant tumors, etc.

Ferritin is excreted from the liver into the bloodstream in all liver diseases, tumors, liver metastases, prolonged use of alcohol, and oral contraceptives. The diagnostic value of this one indicator in the diagnostics of iron deficiency anemia in these cases is small.

The use of ferritin in the diagnostics and monitoring of oncological diseases is based on the fact that in the presence of neoplasms in some organs and tissues there is a violation of iron deposition, which leads to an increase in ferritin in serum, its increased secretion from cells during their death.

Physiological increases in ferritin levels are more pronounced in men than in women, in people on a diet rich in red meat, as well as during intensive hemolysis of blood samples, which is associated with the internal erythrocyte secretion of ferritin.

 

How to prepare for the test?

No specific training is required.

It is recommended to limit alcohol intake, smoking and strenuous physical activity for at least 12 hours before the test.

 

Testing process

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Purchase a test

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