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Ferritin - A water-soluble complex of iron hydroxide with the protein apoferritin, found in liver, spleen, bone marrow cells, reticulocytes and small amounts of blood serum, where it performs the function of transporting iron.
Ferritin concentration depends on iron supply, so this indicator is used to diagnose and monitor iron deficiency or excess, and for the differential diagnostics of anemia.
Ferritin levels rise:
Ferritin levels decrease:
Ferritin also belongs to the acute phase proteins and its normal or increased concentration does not necessarily reflect the deposited iron supply in inflammatory diseases, malignant tumors, etc.
Ferritin is excreted from the liver into the bloodstream in all liver diseases, tumors, liver metastases, prolonged use of alcohol, and oral contraceptives. The diagnostic value of this one indicator in the diagnostics of iron deficiency anemia in these cases is small.
The use of ferritin in the diagnostics and monitoring of oncological diseases is based on the fact that in the presence of neoplasms in some organs and tissues there is a violation of iron deposition, which leads to an increase in ferritin in serum, its increased secretion from cells during their death.
Physiological increases in ferritin levels are more pronounced in men than in women, in people on a diet rich in red meat, as well as during intensive hemolysis of blood samples, which is associated with the internal erythrocyte secretion of ferritin.
No specific training is required.
It is recommended to limit alcohol intake, smoking and strenuous physical activity for at least 12 hours before the test.
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