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Direct bilirubin | Laboratory research

Name: Direct bilirubin | Laboratory research
Brand: სინევო
SKU: 1049
Price: 13.5 GEL
Availability: InStock
Rating: 5 (1 reviews)

Synevo editorial team

Known as: Direct bilirubin | Laboratory research

SKU: 1049

Original price was: ₾15.00.Current price is: ₾13.50.

Study material: Venous blood

Response time (working day): 1

The test is done on an empty stomach: Yes

Home call service: Yes

Country: Georgia

Laboratories❯

General Information

Bilirubin

One of the main components of bile, formed mainly from hemoglobin in erythrocytes. Other sources of bilirubin are myoglobin, cytochromes and heme-containing pigments. When hemoglobin breaks down, free (indirect) bilirubin is initially formed. Free bilirubin is transported from the spleen to the liver along with albumin. In the liver, it binds to glucuronic acid - it is conjugated. As a result, conjugated (direct) bilirubin is formed, which is actively excreted into the bile ducts. Depending on which type of bilirubin concentration increases in the plasma, hyperbilirubinemia is classified as unconjugated and conjugated.

When should we take the test?

Identify and assess the degree of bilirubinemia;
Differential diagnostics of different types of jaundice;
Liver and biliary tract diseases, hemolytic anemia.

Possible interpretation of the results

Increased direct bilirubin concentration:

Hepatitis of various etiologies (acute viral hepatitis, cytomegalovirus-induced hepatitis, infectious mononucleosis, amebiasis, actinomycosis, secondary and tertiary syphilis, acute toxic hepatitis);
Taking hepatotoxic medications;
Biliary tract pathology (cholangitis, cholecystitis);
Oncopathology (primary hepatocarcinoma, metastatic liver damage);
Hereditary hyperbilirubinemia (Dubin-Johnson syndrome, Rotor syndrome);
Hypothyroidism in newborns;
Obstructive jaundice (gallstones, tumors of the pancreas, helminthic invasion);
Biliary cirrhosis (primary or secondary).

Reference values

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Resources

https://spravochnik.synevo.ua/ru/klinicheskaia-himia/bilirubin-frakcionno.html

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This medical information is not intended to be a universal treatment guide for all patients. The treatment process, including the type, volume, and frequency of diagnostic tests and therapeutic procedures, is determined by the physician individually — based on an assessment of the patient's condition and relevant medical indications. The decision is made in consultation with the patient. Before purchasing a test, please read the instructions for its preparation.