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In healthy people, creatinine is normally excreted by the kidneys. Because creatinine excretion is relatively constant in a particular person, the determination of creatinine in the urine may give us an idea of renal function.
Unlike serum creatinine, urinary creatinine concentration can be additionally used as a parameter to determine other urinary metabolites (eg urinary calcium / urinary creatinine, urinary albumin / urinary creatinine, urinary vanillic acid / urinary creatinine, etc.).
Urinary creatinine increases in the following diseases:
Urinary creatinine decreases in the following diseases:
Exercise, pregnancy, and a diet rich in meat can increase urinary creatinine.
Urinary creatinine should be determined not in isolation but in combination with serum creatinine and creatinine clearance to predict renal function status.
No special preparation is required for the test.
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