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In healthy people, creatinine is normally excreted by the kidneys. Because the excretion of creatinine in a particular person is relatively constant, the determination of creatinine in the urine within 24 hours may give us an idea of renal function.
Unlike serum creatinine, urinary creatinine concentration can be additionally used as a parameter to determine other urinary metabolites (eg urinary calcium / urinary creatinine, urinary albumin / urinary creatinine, urinary vanillic acid / urinary creatinine, etc.).
Urinary creatinine increases in the following diseases:
Urinary creatinine decreases in the following diseases:
Exercise, pregnancy, and a diet rich in meat can increase urinary creatinine.
Urinary creatinine should be determined not in isolation but in combination with serum creatinine and creatinine clearance to predict renal function status.
Patient training is not required.
24-hour urine. At 7 o'clock in the morning the patient urinates and does not store this urine, and during the next urination he collects the whole volume of urine in a plastic container (2-3 liter urine container) until 7 o'clock in the morning of the next day (24 hours); The patient should transfer 100 ml of urine from this container (e.g. with a syringe) to a disposable plastic cup for urine and should be stored at 2-8 ° C before the test (1-1,5 h).
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