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Calcium Ca | Laboratory research

Known as: Calcium Ca | Laboratory research
SKU: 1054

Original price was: ₾17.00.Current price is: ₾15.30.

Study material: Venous blood
Response time (working day): 1
The test is done on an empty stomach: Yes
Home call service: Yes
Country: Georgia

General Information

Calcium (Ca) Is a major mineral component of bones. 99% of the body's calcium is in bones and teeth, which is a huge reservoir to maintain serum calcium levels, while the rest is distributed in biological fluids and soft tissues. Calcium ions play an important role in the transmission of nerve impulses, muscle contraction, heart function and coagulation processes.

Hormonal regulation of calcium and phosphorus metabolism is difficult. The small intestine, skeleton, kidneys, and endocrine system, in particular the parathyroid glands, maintain the homeostasis of calcium and phosphorus. Calcium levels in the body are also affected by: calcitonin, vitamin D, estrogens and androgens.

Blood protein levels also affect calcium levels because 45% of serum calcium is bound to protein. Thus, a reduction in serum protein, albumin, reduces the total amount of calcium in the serum.

Abnormal serum calcium levels may indicate parathyroid dysfunction, bone disease, carcinoma, malnutrition, malabsorption syndrome, vitamin D deficiency, and kidney disease. 90% of cases of hypercalcemia occur in hyperparathyroidism. Hypercalcemia is also found in sarcoidosis, adrenal insufficiency and hyperthyroidism and is manifested clinically.

When should we take the test?

  • Once every two years, in patients older than 50 years, for screening for osteoporosis (along with height and weight measurements);
  • During tetany (determining the type of hypocalcemia);
  • Spontaneous fractures, bone pain, bone radiographic changes, growth disorder, dental changes;
  • Nephro- or urolithiasis, nephrocalcinosis, polyuria, polydipsia, chronic kidney disease;
  • Acute pancreatitis, gallstones, recurrent diarrhea, malabsorption;
  • In postoperative thyroidectomy and parathyroidectomy, in diseases of hyperparathyroidism, thyroid gland, testicles, ovaries, adrenal glands;
  • Granulomatous diseases;
  • Tumors;
  • Side effects of certain medications: Vitamin D, A, anticonvulsants, Corticosteroids, thiazides.

The test is prescribed by a doctor.

Possible interpretation of the results

Calcium levels rise:

  • In hyperparathyroidism.
  • Malignant tumors: metastatic cancer of the bone, lung, breast, thyroid, kidney, liver, pancreas, prostate, multiple myeloma, squamous cell carcinoma of the lung or head and neck; 2% of patients with Hodgkin's or non-Hodgkin's lymphoma. Hypercalcemia in these situations is explained by: Bone metastases (multiple myeloma, Burkitt and adult T-cell lymphomas.)
  • Granulomatous diseases (tuberculosis, sarcoidosis).
  • Adverse drug reactions (vitamin D poisoning, diuretics, other therapeutic agents).
  • Chronic renal failure.
  • Other endocrine disorders: hyperthyroidism, hypothyroidism, adrenal insufficiency, acromegaly, pheochromocytoma, multiple endocrine neoplasia syndrome (MEN).
  • Acute osteoporosis.
  • Various causes: familial hypocalcemia hypercalcemia, porphyria, dehydration with hyperproteinemia, hypophosphatemia, idiopathic hypercalcemia in infants.

Calcium levels decrease:

  • Pseudohypocalcemia, which reflects a decrease in albumin levels.
  • Surgical, post-traditional, idiopathic hypoparathyroidism; Parathyroid infiltration for various reasons (sarcoidosis, amyloidosis, hemochromatosis, tumor); Congenital syndromes (Dijorgi syndrome).
  • Pseudohypoparathyroidism.
  • Malabsorption of calcium and vitamin D in dysfunction of the spleen, celiac disease, pancreas.
  • Obstructive jaundice.
  • Chronic renal failure with uremia and hyperphosphatemia; Fanconi syndrome; Renal tubular acidosis;
  • Acute pancreatitis with fatty necrosis.
  • Decreased intake of calcium, phosphorus and vitamin D (hunger, malnutrition, bone disease, last trimester of pregnancy);
  • Taking medications (tumor chemotherapy, fluoride poisoning, antibiotics, loop diuretics, anticonvulsants, corticosteroids, calcitonin, multiple blood transfusions, excess intravenous fluid intake (reduces albumin levels).
  • Hypomagnesemia.
  • Tumors with osteoblastic metastases (breast, prostate, lung, thyroid).
  • Toxic shock syndrome.
  • Tumor lysis syndrome.

Additional information

How to prepare for the test?

The test is recommended on an empty stomach.

Note: Do not take calcium supplements for 8-12 hours before the test;

Testing process

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Purchase a test

Submission of material

Results Online Consult a doctor

Results Online

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Resources

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