Aspergillus Aspergilus Fumigatus | Antibodies IgA, IgM, IgG

General Information

There are more than 200 species of fungi in the genus Aspergillus, but only about 20 are pathogenic to humans, the most aggressive of which is Aspergillus Fumigatus. Aspergillus Fumigatus spreads through spores that are resistant to environmental factors such as heat, dehydration, chemical exposure, radiation, and more for months.

People with normal immune status rarely develop fungal infections, but immunocompromised people are at high risk of developing aspergillosis. The main risk factor for developing aspergillosis is neutropenia (a deficiency of neutrophils in the blood), which can occur in various pathologies:

• Acute leukemia
• Solid tumors
• Organ transplantation
• Bone marrow transplant
• Primary immunodeficiency
• Chronic lung diseases: tuberculosis, cystic fibrosis, chronic bronchitis, etc.

Aspergillosis is diagnosed by detecting antibodies to its cellular glycoprotein (galactomannan antigen).

Serological tests for Aspergillus are particularly important for the diagnostics of localized Aspergillus infections and allergic bronchopulmonary aspergillosis (ABPA).

Preparation of the patient: it is not necessary

Material for examination: Venous blood