Vitamin H | Laboratory research

General Information

Vitamin H, aka biotin, aka vitamin B7, is a water-soluble vitamin that is part of the B complex. Unlike other vitamins that the body gets from food, biotin is produced in the large intestine with the participation of bacterial flora. Biotin plays an important role in the inclusion of CO2 in the metabolism of lipids, carbohydrates and proteins and performs the function of an enzyme cofactor (catalyst).

Biotin also participates in the metabolism of niacin (vitamin B3), the degradation processes of amino acids, the formation of purines (a product of nucleic acids) and others.

Along with vitamins A, B2, B6, it also protects the skin and hair. Vitamin H prevents the accumulation of cholesterol in the endothelium of blood vessels, it also participates in the release of toxic substances and metabolites, thereby contributing to the proper functioning of the liver and gall bladder.

Guillotine improves memory; It is used in the complex treatment of alcoholism, atherosclerosis, hypercholesterolemia, diabetes, fatty liver, diseases of the gastrointestinal tract, weight correction.

Foods containing vitamin H include: meat, especially liver and kidney, dairy products, egg yolks, seafood, fish, avocados, bananas, strawberries, legumes, nuts, citrus fruits, cereals and others. Vitamin H (Biotin, Vitamin B7) is thermoremedial, although it is sensitive to heat and light.

The recommended daily dose of vitamin H is 300 ng for healthy adults, and 350 ng for pregnant and lactating mothers.

Deficiency of vitamin H in the body is rare, however, it is usually associated with its lack in food or malabsorption. Violation of vitamin H metabolism is mainly related to genetic deficiency of enzymes. The most common cause of biotin metabolism disorders is deficiency of enzymes - biotinidase and holocarboxylase-synthetase.

Deficiency of biotin-dependent enzymes - pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase and acetyl-CoA carboxylase leads to multiple carboxylase deficiency, which causes life-threatening pathologies. Disruption of biotin supply leads to irreversible mental and neurological disorders.

Symptoms

Weakness

Anorexia

Nausea

Vomiting

Anemia

alopecia (baldness)

Seborrheic dermatitis

Very dry or very oily skin

Injuries of the mucous membrane of the mouth and throat

Glossit

myalgia (muscle pain)

Hyperesthesia (pathologically enhanced sensory perception)

Conjunctivitis

Depressive episodes

Hearts

Material for examination: Venous blood

Preliminary preparation: The study is conducted on an empty stomach. It is not recommended to drink alcohol for 24 hours before the study

Reference norm:   >200 ng/l

Interpretation of results: of plasma biotin  A lower than normal value may indicate malnutrition or a deficiency of enzymes involved in biotin metabolism. Antibiotics and anticonvulsants reduce plasma biotin content