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Saccharomyces cerevisiae | As IgA, IgM (Crohn's disease, ulcerative colitis)

Known as: Saccharomyces cerevisiae antibodies IgA, IgM
SKU: 725

150.00

Not in stock

Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: no
Home call service: Yes
Country: EU

General Information

anti- Saccharomyces cerevisiae (ASCA) antibodies are immune proteins that are often found in people who have  They have inflammatory bowel diseases.

Saccharomyces cerevisiae Food products contain yeast fungi. Saccharomyces cerevisiae The relationship between the presence of antibodies and autoimmune inflammatory processes of the intestine is still unclear.

The symptoms and severity of inflammatory bowel diseases are different in different patients and may change over time. Crohn's disease and ulcerative colitis are the most common inflammatory bowel diseases. Crohn's disease can affect any part of the gastrointestinal tract, while ulcerative colitis affects the large intestine. These diseases are usually diagnosed by endoscopic examination and examination of intestinal biopsy material.

Saccharomyces cerevisiae Antibodies are more common in Crohn's disease than in ulcerative colitis.

Saccharomyces cerevisiae There are two classes of antibodies: IgA and IgG. IgG determines the course of the disease and the course of treatment.

When should we take the test?

Why is the test conducted??

For differential diagnostics between Crohn's disease and ulcerative colitis.

 

When is the test conducted?

The study is conducted in such symptoms as:

Diarrhea

stomach-ache

Bleeding from the intestine

Fever

common weakness

Bone, skin, joint and other organ symptoms

Mental and developmental retardation in children

Possible interpretation of the results

 

 

 

ASCA antibody results are usually considered together with pANCA test results:

  • If ASCA antibodies are positive and pANCA is negative, it is highly likely that Crohn's disease is the diagnostics.
  • If ASCA antibodies are negative and pANCA is positive, this indicates ulcerative colitis.

Negative values ​​of ASCA and pANCA antibodies do not rule out inflammatory bowel diseases.

In addition to the mentioned antibodies, it is sometimes necessary to study such tissue antibodies as: anti-CBir1 (anti-flagellin antibodies) and anti-OMP C (anti-outer membrane cation antibodies). The presence of anti-CBir1 and anti-OMP C antibodies indicates Crohn's disease.

Positive indicators of multiple antibodies indicate an aggressive course of the disease.

The ASCA antibody test is produced only once. There is no sacrifice for repeated research. ASCA IgA and IgG tests are performed simultaneously.

Reference values

Material for examination: Venous blood

Preliminary preparation: it is not necessary

 

Primary diagnostics of inflammatory bowel diseases is based on instrumental research and biopsy results, however, in some cases it is still difficult to distinguish between ulcerative colitis and Crohn's disease with these research methods.

Anti-Saccharomyces cerevisiae antibodies are often tested for perinuclear antineutrophil cytoplasmic antibodies (pANCA).

The presence of Saccharomyces cerevisiae antibodies is more typical for Crohn's disease, and pANCA for ulcerative colitis.

Additional information

Testing process

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