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Determination of 17-hydroxycorticoid in urine
17-OH-corticosteroids are produced by the metabolism of cortisol in the liver and other tissues. Determination of 17-OH-corticosteroids in urine is used to estimate the amount of cortisol produced. The test is often used in the diagnostics of Cushing's syndrome.
Research material
24 hour urine
How to prepare for the test
Before collecting a urine sample, it is recommended to stop taking such medications as:
contraceptives
Antibiotics
Glucocorticoids
Indicators of the norm (24 in an hourly urine sample)
0-2 years - 2.0 - 4.0 mg/24 hours
2-6 years - 3.0 - 6.0 mg/24 hours
6-10 years - 4.0 - 8.0 mg/24 hours
10-14 years - 4.0 - 10.0 mg/24 hours
Women 14-99 years old – 4.0 – 14.0 mg/24 hours
Men 14-99 years old – 7.0 – 19.0 mg/24 hours
17OH- An increase in the corticoid level characterizes the following pathologies:
Cushing's syndrome caused by adrenal gland tumor - hyperproduction of cortisol
depression
Treatment with hydrocortisone
Malnutrition
obesity
pregnancy
Arterial hypertension caused by hormonal reasons
extreme physical and emotional stress
Pituitary tumor with excess production of adrenocorticotropic hormone
17OH-Decreasing the corticoid level characterizes the following pathologies:
Adrenal gland failure (not producing enough cortisol)
In the case of functional failure of the pituitary gland - with a decrease in the production of adrenocorticotropic hormone
Congenital enzyme deficiency
The condition after the surgical removal of the adrenal gland
During polyuria (more than 3 liters of urine per day), an excess of cortisol products may be observed, while it is actually within the normal range.
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30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2024, the Synevo Georgia network will include 3 clinical laboratories and 56 blood sampling units, which will perform more than 300,000 tests.
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