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A & B toxins of Clostridium difficile (feces)

Known as: Clostridium difficile
SKU: 1648


Research material: Stools
Response time (working day): 1-2
The test is done on an empty stomach: no
Home call service: Yes
Country: Georgia

General Information

Clostridium difficile  (Clostridium difficile) Is a bacterium that can cause both a mild symptom - e.g. Diarrhea, Also Colling - a life-threatening inflammation of the large intestine.
Clostridium difficile-Colitis is the result of disruption of the normal intestinal flora. This time occurs in the intestine C. difficile-T. Colonization and excretion of toxins (A and B) that cause inflammation of the mucous membrane, damage and diarrhea.

Clostridium difficile disease, often found in hospitalized adults. Infection can be caused by treatment with antibiotics. However, studies have shown that Clostridium difficile infection is more common in young people, and in people who have not received antibiotics and have not been hospitalized.

Clostridium difficile disease develops within a few months of taking antibiotics.

When should we take the test?

  • In any patient with diarrhea who has received antibiotic therapy in the last 2 months and / or diarrhea started 72 hours (or more) after hospitalization. We need to be skeptical before making an accurate diagnostics difficultOn colitis caused by.
  • Severe diarrhea syndrome - defecation at least 3 times in 24 hours with watery stools;
  • During diarrhea caused after long-term treatment with antibiotics.
  • Diarrhea in immunocompromised patients and patients undergoing chemotherapy.


Symptoms of a mild to moderate infection:

  • Liquid diarrhea three or more times a day for 2-3 days or more.
  • Mild care pain in the abdomen and pain on touch.

Symptoms of severe ongoing infection

In severe cases, some people experience dehydration and require hospitalization. Clostridium difficile causes inflammation of the colon - colitis, damages the intestinal tissue, resulting in bleeding or purulent discharge (pseudomembranous colitis). Symptoms of a severely ongoing infection include:

  • Liquid diarrhea 10-15 times a day.
  • Convulsions and pain in the abdomen, which can be severe
  • Heat
  • Blood or pus in the stool
  • nausea
  • Dehydration
  • Despair
  • Weight loss
  • Swelling in the abdomen
  • Kidney failure
  • Increase in white blood cells (leukocytes) in feces.

Additional information

How Get ready For the test / Of the material Collection rules

Bacteriological examination of feces should be performed as soon as possible after the onset of the disease and before starting any antimicrobial treatment.

  • No special training is required for the study.
  • The test material is collected in a sterile container with a screw cap and a material collection spoon cap.
  • In research, feces should not contain impurities such as urine, so you should urinate before collecting feces to rule out the possibility of urine entering the stool.
  • Stools are collected from a sterile surface - the so-called. Night pot or "sudno", which is well washed with soap, rinsed several times with tap water, and then treated with boiling water and cooled. It is forbidden to treat the surface of the pot with disinfectants.
  • The test material is taken mainly from the middle portion of the feces, with a special spoon mounted on the lid of a sterile container in the amount of not more than 1/3 of the volume of the container (up to 10 grams - 1 teaspoon).
  • When collecting, be sure to collect the liquid part of the material - especially the mucous and bloody parts, if any.
  • Do not fill the container to the brim!
  • The analysis should preferably be performed on newly excreted feces Pattern From taking the maximum 1 For hours. If this is not possible, the sample is stored at 2-8 ° C Max 1 during the day.
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