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Plasminogen activity

Also known as: plasminogen activity
SKU: 1471

107.00

Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: Yes
Home call service: Yes
Country: EU

General Information

Plasminogen is synthesized in the liver and circulates in 2 main forms: GLU-plasminogen (containing a glutamic acid residue) and LYS-plasminogen. Tissue plasminogen activator converts inactive plasminogen into active plasmin. In addition, urokinase plasminogen activator, coagulation factors XIa and XIIa participate in the conversion of plasminogen into plasmin.

Plasmin is a protease enzyme and participates in fibrin decomposition.

Plasminogen deficiency is a genetically determined autosomal recessive pathology.

 

Assessment of plasminogen activity reflects various potential defects.

Possible interpretation of the results

Referral norms are different in different ethnic groups.

The normal concentration of plasminogen in newborns is much lower.

Additional information

Chromogenic study of plasminogen: is a semi-functional study of plasminogen activity. During the study, plasminogen is activated through streptokinase, which converts it into plasmin. A plasminogen functional assay determines whether plasminogen deficiency is present. If the functional test reveals a reduced activity of plasminogen, then an antigen test is performed to detect the first and second type of disorder.

Testing process

Purchase a test Submission of material

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Submission of material

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