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Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: no
Home call service: YesAnti-Saccharomyces cerevisiae (ASCA) antibodies are immune proteins that are often found in people with inflammatory bowel disease.
Saccharomyces cerevisiae are yeast fungi found in food products. The relationship between the presence of Saccharomyces cerevisiae antibodies and autoimmune inflammatory processes of the intestine is still unclear.
The symptoms and severity of inflammatory bowel diseases are different in different patients and may change over time. Crohn's disease and ulcerative colitis are the most common inflammatory bowel diseases. Crohn's disease can affect any part of the gastrointestinal tract, while ulcerative colitis affects the large intestine. These diseases are usually diagnosed by endoscopic examination and examination of intestinal biopsy material.
Saccharomyces cerevisiae antibodies are more common in Crohn's disease than in ulcerative colitis.
There are two classes of Saccharomyces cerevisiae antibodies: IgA and IgG. IgG determines the course of the disease and the course of treatment.
Why is the test conducted??
For differential diagnostics between Crohn's disease and ulcerative colitis.
Study material: Venous blood
Preliminary preparation: not necessary
How is research used?
Primary diagnostics of inflammatory bowel diseases is based on instrumental research and biopsy results, however, in some cases it is still difficult to distinguish between ulcerative colitis and Crohn's disease with these research methods.
Anti-Saccharomyces cerevisiae antibodies are often tested for perinuclear antineutrophil cytoplasmic antibodies (pANCA).
The presence of Saccharomyces cerevisiae antibodies is more typical for Crohn's disease, and pANCA for ulcerative colitis.
The study is conducted in such symptoms as:
Diarrhea
stomach-ache
Bleeding from the intestine
Fever
common weakness
Bone, skin, joint and other organ symptoms
Mental and developmental retardation in children
ASCA antibody results are usually considered together with pANCA test results:
• If ASCA antibodies are positive and pANCA is negative, Crohn's disease is highly likely to be the diagnostics.
• If ASCA antibodies are negative and pANCA is positive, this indicates ulcerative colitis.
Negative values of ASCA and pANCA antibodies do not rule out inflammatory bowel diseases.
In addition to the mentioned antibodies, it is sometimes necessary to study such tissue antibodies as: anti-CBir1 (anti-flagellin antibodies) and anti-OMP C (anti-outer membrane cation antibodies). The presence of anti-CBir1 and anti-OMP C antibodies indicates Crohn's disease.
Positive indicators of multiple antibodies indicate an aggressive course of the disease.
The ASCA antibody test is produced only once. There is no sacrifice for repeated research. ASCA IgA and IgG tests are performed simultaneously.
Material for examination: Venous blood
Preliminary preparation: it is not necessary
How is research data used?
Primary diagnostics of inflammatory bowel diseases is based on instrumental research and biopsy results, however, in some cases it is still difficult to distinguish between ulcerative colitis and Crohn's disease with these research methods.
Anti-Saccharomyces cerevisiae antibodies are often tested for perinuclear antineutrophil cytoplasmic antibodies (pANCA).
The presence of Saccharomyces cerevisiae antibodies is more typical for Crohn's disease, and pANCA for ulcerative colitis.
Testing process
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
Contact information
Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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