Country: EU
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₾145.00
Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: Yes
Home call service: Yes11-Deoxycortisol is a precursor of cortisol. Its levels increase significantly when the concentration of adrenocorticotropic hormone is significantly increased (e.g., in Cushing's syndrome, corticotropin-secreting tumors, etc.) or in 11-beta-hydroxylase deficiency.
Determination of 11-deoxycortisol in serum or determination of 17-ketosteroids in urine against the background of metyrapone blockade – used to determine hypothalamic-pituitary-adrenal connections, for differential diagnostics of Cushing's syndrome, etc.
Cushing's syndrome (high cortisol)
Addison's disease (low cortisol)
Elevated serum 11-deoxycortisol in suspected congenital adrenal hyperplasia indicates a possible 11-beta-hydroxylase (enzyme) deficiency. However, in some patients, an increase in serum 11-deoxycortisol may not be detected. In a number of cases, an increase in serum 11-deoxycortisol concentration is observed only in response to stimulation with adrenocorticotropic hormone.
Material for examination:Venous blood
Warning:Ethyl alcohol, estrogens, barbiturates, valproic acid, phenytoin, exogenous glucocorticoids cause a change in the response to the metyrapine test.
Testing process
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| Purchase a test | Submission of material |
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| Results Online | Consult a doctor |
