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₾235.00
Study material: Venous blood
Response time (working day): 14
The test is done on an empty stomach: Yes
Home call service: YesAldosterone is an important hormone produced by the adrenal cortex. The hormone stimulates sodium reabsorption and potassium excretion by the kidney. Renin is an enzyme that is synthesized by the kidneys and controls the activation of angiotensin, which stimulates the release of aldosterone by the adrenal gland.
Renin secretion by the kidney is activated in response to a decrease in blood pressure or a decrease in sodium chloride concentration in the renal tubules. Renin converts the blood protein - angiotensinogen to angiotensin I, which is then converted to angiotensin II, which provides narrowing of the blood vessel wall and stimulation of aldosterone release. This is followed by an increase in blood pressure. It also maintains normal levels of sodium and potassium.
A number of conditions lead to overproduction or underproduction of aldosterone.
Aldosterone and renin studies are important to determine whether the adrenal gland is producing enough aldosterone. Aldosterone research is performed in blood serum or 24-hour urine. Renin research is performed only in serum.
Aldosterone and renin concentrations are high in the morning and fluctuate more or less throughout the day, depending on stress, medications, body position, and other factors.
The study of blood aldosterone and renin is carried out at the same time, in case of high arterial hypertension, especially in case of potassium deficiency. Primary hyperaldosteronism is a potentially curable form of hypertension, so early detection and treatment are important.
An aldosterone study is prescribed along with other studies when adrenal insufficiency or Addison's disease is suspected.
Since the level of aldosterone in the blood varies during the day, determination of aldosterone in 24-hour urine is often performed.
| disease | Aldosterone | Cortisol | renin |
| Primary aldosteronism (Connie's disease) | high | norm | Low |
| Secondary aldosteronism | high | norm | high |
| Adrenal gland failure (Addison's disease) | Low | Low | high |
| Cushing's syndrome | Low | high | Low |
Primary aldosteronism (Connie's disease) is caused by hyper (excess) production of aldosterone by the adrenal gland. The most common cause is a tumor of the adrenal gland. High levels of aldosterone increase renal tubular sodium reabsorption and potassium loss, often resulting in electrolyte imbalance.
Symptoms include: high blood pressure, headache, muscle weakness, low potassium levels in the blood (hypokalemia). Along with aldosterone, it is often necessary to measure cortisol levels.
Secondary aldosteronism It is more common than primary and may develop for various reasons, for example: in response to decreased blood flow to the kidney tissue, arterial hypotension, or decreased sodium levels in the blood. Secondary aldosteronism occurs in congestive heart failure, liver cirrhosis, renal artery stenosis, and toxic pregnancy. It can also develop during dehydration.
Hypoaldosteronism As a rule, it develops against the background of adrenal gland failure. This leads to dehydration (due to loss of sodium), a decrease in blood pressure, a decrease in sodium concentration in the blood, and an increase in potassium.
Before the aldosterone and renin test, you should avoid stress, alcohol and some medications.
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
☎️ Hotline: 239 38 33 or 239 40 65
577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
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Address: Tsinandali St. N9 (N1 Clinical Hospital area)
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