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Magnesium Mg | Laboratory research

Known as: Magnesium Mg
SKU: 1058

13.50

Study material: Venous blood
Response time (working day): 1
The test is done on an empty stomach: no
Home call service: Yes
Country: Georgia

General Information

Magnesium (Mg) Is a chemical element that is included in the composition of cells. The bones contain 70% of the total amount of magnesium along with Ca and P, the rest of the magnesium is found in the body in erythrocytes, muscles, liver and other organs and tissues, it is part of many enzymes.

When should we take the test?

  • Assessment of renal function;
  • Nervous system disorders (increased neuromuscular excitability, tetany, seizures, muscle hypotension);
  • Electrolyte metabolism disorders (hypocalcemia, hypokalemia)
  • Diseases of the cardiovascular system (heart failure, left ventricular hypertrophy, ventricular arrhythmia);
  • Monitoring of patients treated with nephrotoxic drugs;
  • Malabsorption syndrome, parenteral nutrition.

Possible interpretation of the results

  • Iatrogenic causes: uncontrolled use of magnesium preparations; Poisoning with lithium carbonate, salicylates;
  • Renal failure;
  • Dehydration;
  • Diabetic coma before treatment;
  • Hypothyroidism;
  • Addison's disease;
  • Condition after removal of the adrenal glands;
  • Accidental intake of large amounts of sea water.

Magnesium concentration decreases:

  • Diseases of the digestive system: malabsorption or excessive loss of fluid through the gastrointestinal tract;
  • Kidney diseases: chronic glomerulonephritis, pyelonephritis, tubular renal acidosis, diuretic phase of acute tubular necrosis, postobstructive diuresis, osmotic diuresis (mannitol, glucose, urea);
  • Eating Disorders: Acute alcoholism and alcoholic cirrhosis of the liver, prolonged parenteral fluid intake containing magnesium, metabolic acidosis;
  • Endocrine disorders: Hypercalcemia associated with hyperthyroidism; Hyperparathyroidism, diabetes mellitus, hyperaldosteronism, syndrome with impaired secretion of antidiuretic hormone;
  • Metabolic disorders: excessive lactation, the last trimester of pregnancy, insulin treatment of diabetic coma;
  • Other situations: Toxicity during pregnancy or eclampsia, osteolytic tumors of the bone, progressive Paget's disease of the bone, acute and chronic pancreatitis, blood transfusion with citrate, hemodialysis, severe burns, sweating, septic condition, hypothermia.

Additional information

The higher the metabolic activity of the cell, the more magnesium it contains. Magnesium is most important for the functioning of the heart, nerve and muscle tissue. About 1% is in plasma, 25% is bound to proteins, and the rest remains in ionized form - Mg2+. Most of the magnesium is in the mitochondria and in the nucleus.

In addition to the plastic role that magnesium plays as an integral component of bones and soft tissues, it plays the role of activator of more than 300 enzymes involved in carbohydrate metabolism and the synthesis of proteins and nucleic acids.

Na+, K+ And Ca2 ++ Along with ions, magnesium is involved in the mechanism of neuromuscular excitability and blood coagulation. The actions of calcium and magnesium are closely related to each other, a deficiency of one of the two elements significantly affects the metabolism of the second element (magnesium is essential for both intestinal absorption of calcium and its metabolism).

Magnesium acts as a calcium antagonist in muscle cells. Magnesium deficiency causes the mobilization of calcium from the bones, which may lead to abnormal calcifications in the aorta and kidneys, so it is recommended to consider calcium levels when assessing magnesium levels.

Hypomagnesemia is also associated with hypokalemia in 60% of cases. Clinically, magnesium deficiency causes neuromuscular diseases (muscle weakness, tremor, tetany, and seizures) and can also lead to arrhythmias.

 

How to prepare for the test?

No specific training is required.

It is recommended to limit alcohol intake, smoking and strenuous physical activity for at least 12 hours before the test.

 

Testing process

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