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Gammaglutamyltransferase (GGT)

Name: Gammaglutamyltransferase (GGT)
Brand: სინევო
SKU: 1051
Price: 13.5 GEL
Availability: InStock
Rating: 5 (1 reviews)

Known as: Gammaglutamyltransferase (GGT)

SKU: 1051

₾13.50

Study material: Venous blood

Response time (working day): 1

The test is done on an empty stomach: Yes

Home call service: Yes

Country: Georgia

Laboratories❯

General Information

GGT - gammaglutamyltranspeptidase, gammaglutamyltransferase - is an enzyme that is mainly found in the kidneys, liver, pancreas and less so in other tissues.

GGT synthesis can be induced by hepatic cholestasis, chronic alcohol consumption, and therapeutic doses of drugs such as phenytoin. GGT levels are elevated in hepatocytes during hepatoma, in hepatocytes compressed by liver tumors, and in cirrhotic liver regenerative areas. Increased serum GGT levels are also caused by damage to the cell membrane by toxins (including alcohol), ischemia, infections. GGT is a specific enzyme in the liver and bile ducts.

When should we take the test?

GGT is a diagnostic marker of damage to the hepatobiliary system (liver, bile ducts) and is defined in the following diseases:

Acute viral hepatitis caused by hepatitis A, B, C, E viruses;
Acute hepatitis caused by other viruses - e.g. EBV, CMV;
Chronic hepatitis;
cirrhosis of the liver;
Gallbladder disease;
Cholecystitis and cholangitis;
Jaundice - GGT is an important indicator of the cause of jaundice - liver disease or obstruction of the bile ducts by stones (stones), liver tumors, or by the pancreas;
Autoimmune diseases of the liver;
Autoimmune diseases of the biliary tract - primary biliary cirrhosis, primary sclerotic cholangitis;
Chronic Alcohol Abuse - GGT is the most sensitive indicator of prolonged alcohol consumption.
Long-term therapy with medications such as phenobarbital, phenytoin and others.

Alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), total and direct bilirubin fraction are usually determined in conjunction with GGT.

The importance of GGT is more informative for biliary system diseases (cholecystitis, cholangitis, obstructive jaundice) than the importance of ALP because it increases earlier and lasts longer.

Possible interpretation of the results

In acute viral hepatitis, GGT is increased in smaller amounts than other liver enzymes (AST, ALT);
The increases in GGT and ALP are usually parallel. A significant increase in GGT is found during biliary system obstruction;
In cirrhosis of the liver the rate may increase by 2-10 times;
Higher rates are also observed in hepatic steatosis (fatty liver), chronic hepatitis, primary biliary cirrhosis, and primary sclerotic cholangitis;
The degree of increase in GGT during alcoholism depends on the duration of abuse and the amount taken. Enzyme levels gradually decrease after cessation of alcohol consumption but remain above normal for a long time.
Acute pancreatitis;
Acute myocardial infarction;
Acute renal failure;
Diabetes mellitus (slightly elevated);
Tumors (slight increase);
Cerebral hemorrhages (slight increase).

Additional information

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Testing process


Purchase a test	Submission of material


Results Online	Consult a doctor

Resources

ГГТ / GGT – Gammaglutamyl transferase test

Gamma-glutamyltransferase (Glutamyltranspeptidase)

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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.

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48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.

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30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.

More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.

More than 3000 diagnostic tests

More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.

National Network of "Synevo" European Laboratory

30 laboratory centers in Georgia: Tbilisi, Kutaisi, Batumi, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi.

More than 60000 patients each year.

Synevo service is always available for up to 5000 patients.

"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.