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Amylase Is a hydrolytic enzyme that breaks down starch and glycogen into maltose. Amylase is produced mainly in the salivary glands and pancreas, then passes into the oral cavity or duodenal lumen and participates in the digestion of carbohydrates. In blood serum, pancreatic and salivary amylase isoenzymes are isolated from each other. Significantly low amylase activity is also present in organs such as the ovaries, fallopian tubes, small and large intestines, and liver, although serum detects only pancreatic (40%) and salivary (60%) amylase.
Amylase levels can be increased in a number of diseases that have a clinical picture similar to acute pancreatitis (acute appendicitis, peritonitis, perforated gastric ulcer, intestinal obstruction, cholecystitis, mesenteric vascular thrombosis, periocytosis, fecal incontinence).
The increase in amylase activity is in most cases reactive. In acute pancreatitis, blood and urine amylase activity increases 10-30 times 4-6 hours after the onset of the disease, reaches a maximum after 12-24 hours and rapidly decreases and returns to normal on days 2-6. Increased serum amylase levels are not associated with the severity of pancreatitis.
Amylase can form large complexes with immunoglobulins and other plasma proteins (macroamylase), so it cannot pass into the renal glomeruli. At the same time, when the amylase content in the serum increases, its normal activity is observed in the urine.
Amylase activity in pancreatic cancer increases slightly or remains at normal levels, so the test is not very informative for diagnosing pancreatic cancer.
With the following symptoms:
No special preparation is required for the test.
The test should be performed on an empty stomach.
Venous blood
Alpha-amylase concentration increases:
Alpha-amylase concentration decreases:
https://spravochnik.synevo.ua/ru/klinicheskaia-himia/alpha-amylase.html
https://www.synevo.bg/amilaza/
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More than 1000 routine and complex/specific diagnostic tests in all major areas of clinical pathology.
48 laboratory centers in 25 cities of Georgia: Tbilisi, Rustavi, Kutaisi, Batumi, Marneuli, Telavi, Zugdidi, Zestafon, Gori, Kobuleti, Akhaltsikhe, Khashuri, Sartichala, Kazbegi, Borjomi, Samtredia, Gurjaani, Lagodekhi, Akhmeta, Ozurgeti, Poti, Chiatura , Dusheti, Kareli, New Gudauri.
Use the Synevo web platform to view results from anywhere and anytime
Use the Synevo web platform to view results from anywhere, anytime
From Monday to Saturday you can use the laboratory services at home.
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577293008 (9:00-დან 17:00-მდე)
30 laboratory centers in 11 cities of Georgia: Tbilisi, Kutaisi, Batumi, Kobuleti, Zugdidi, Zestaponi, Rustavi, Marneuli, Akhaltsikhe, Telavi, Gori.
More than 3000 routine and complex / specific diagnostic tests in all major areas of clinical pathology.
"Synevo" - Providing a wide range of diagnostic services in Georgia, offering more than 1,000 routine and specific diagnostic tests in all major areas of clinical pathology. By the end of 2023, the Synevo Georgia network will include 3 clinical laboratories and 47 blood sampling units, which will perform more than 300,000 tests.
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